Case Report
Volume 19 Issue 2 - 2020
Sutton's Disease and Vitamin Deficiency: Diagnostic and Therapeutic Difficulties. About a Clinical Case at the University Teaching Hospital Center of Yaounde
Ntep Ntep David Bienvenue*, Bengondo Messanga Charles, Kenna Ernest, Mendouga Menye Coralie, Sitchepi Kamsu Huguette Sonia and Endalle Catherine
Department of Odontostomatology and Maxillofacial Surgery, Yaounde University, Teaching and Hospital Center, Cameroon
*Corresponding Author: : Ntep Ntep David Bienvenue, Department of Odontostomatology and Maxillofacial Surgery, Yaounde University, Teaching and Hospital Center, Cameroon.
Received: December 02, 2019; Published: January 03, 2020


Sutton's disease is a major recurrent aphthous stomatitis. It is an inflammatory pathology, characterized by the recurrent eruption of ulcerations. 

Although the etiopathogenesis of sutton's disease is still imperfectly known, it is nevertheless probable that the main phenomenon results from the cytotoxic action of CD4+ and CD8+ T lymphocytes and monocyte-macrophages with respect to the oral epithelium. 

We report the case of a 22-year-old patient who came to see for recurrent ulcerations of the oral cavity. The endobuccal examination showed giant ulcers of the lower lip, tongue and uvula. 

The suggested diagnostic for this clinical picture were: aphthous oral recurrent, cyclic neutropenia and vitamin B12 deficiency. The combination of low cyanocobalamin, megaloblastic anemia and histopathological characteristics, confirmed the diagnosis of Sutton disease secondary to vitamin B12 deficiency. 

Several treatments have been tried but cannot prevent recurrence. However, taking colchicine combined with vitamin B12 replacement therapy reduced the frequency and severity of the lesions. 

Keywords: Sutton's Disease; Vitamin B12


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Citation: Ntep Ntep David Bienvenue., et al. “Sutton's Disease and Vitamin Deficiency: Diagnostic and Therapeutic Difficulties. About a Clinical Case at the University Teaching Hospital Center of Yaounde”. EC Dental Science 19.2 (2020): 01-07.

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