Review Article
Volume 19 Issue 2 - 2020
Quorum Sensing - Polymicrobial Challenge in Periodontics
Sangeetha S1, Padma Lochani1, Jayashree Tukaram Kshirsagar1, Sai Sarath Kumar1 and C Burnice Nalina Kumari2*
1Department of Periodontology, Tamil Nadu Government Dental College and Hospital, Chennai, India
2Department of Periodontology, Meenakshi Ammal Dental College, Chennai, India
*Corresponding Author: C Burnice Nalina Kumari, Associate Professor, Department of Periodontology, Meenakshi Ammal Dental College, Chennai, India.
Received: December 16, 2019; Published: January 07, 2020


Periodontal disease is a multifactorial disease caused by imbalance between complex microbial community and the host immune response. Plaque provides favorable environment for the survival and growth of microorganisms inducing periodontal disease. The current concept of biofilm formation and cell to cell communication of microorganisms present in the biofilm occurs by the production of chemical signaling molecules which has become the niche for molecular level research projects. This biological process is called quorum sensing which modulates the expression of genes involved in survival, biofilm formation, virulence and pathogenicity of microorganisms. To eradicate this communication, quorum quenchers play a role in the inhibition of signals of quorum sensing. This review article enlightens the quorum sensing signaling and the magical action of quorum quenchers from the data collected by different analysis.

Keywords: Quorum Sensing; Quorum Quenching; Bacterial Communication


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Citation: C Burnice Nalina Kumari., et al. “Quorum Sensing - Polymicrobial Challenge in Periodontics". EC Dental Science 19.2 (2020): 01-08.

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