Research Article
Volume 19 Issue 2 - 2020
Aswin Prasad S1 and KL Vandana2*
1Consulting Periodontist and Implantologist, Vaidyanatheshwara Dental Empire (Davangere, Karnataka), Valluvanad Hospital (Ottappalam, Kerala), Kerala, India
2Senior Professor, College of Dental Sciences, Davangere, Karnataka, India
*Corresponding Author: KL Vandana, Senior Professor, College of Dental Sciences, Davangere, Karnataka, India.
Received: November 18, 2019; Published: January 08, 2020


Aim: The study aimed to evaluate the clinical parameters and gingival crevicular fluid (GCF) levels of SA (sialic acid) and CS (chondroitin sulfate of glycosaminoglycans) in dental fluorosed patients with and without periodontitis.

Materials and Methods: A total of 40 patients were selected and clinical parameters were assessed. The GCF-SA and CS levels were estimated. The selected patients were permanent residents of endemic fluorosis belt in and around Davangere.

Results: The overall group wise estimation of GCF SA showed significantly higher SA levels in the FD group (p < 0.005), whereas the GCF CS levels showed no significant difference between FH and FD group (p = 0.886).

Conclusion: The grade wise dental fluorosis assessment of periodontal clinical and biochemical parameters (GCF- SA and CS) revealed similar features between fluorosed healthy and diseased (periodontitis) patients. However, overall comparison between the fluorosed healthy and diseased patients showed significant changes in diseased group.

Clinical Relevance: Dental fluorosis is known to bring about changes in both during health and periodontal disease status. The estimation of biochemical parameters like GCF SA and CS support the routine periodontal clinical changes.

Keywords: Dental Fluorosis; Periodontium; Health; Periodontitis; Sialic Acid; Chondroitin Sulfate


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Citation: Aswin Prasad S and KL Vandana. “Evaluation of Periodontal Clinical and Biochemical (GCF-Sialic Acid and Chondroitin Sulfate) Parameters in Various Grades of Fluorosis in Patients with Periodontitis”. EC Dental Science 19.2 (2020): 01-12.

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