Review Article
Volume 20 Issue 12 - 2021
Bioresorbable Fixation of Facial Trauma: An Overview
Hisham Abbas Komo1*, Marwan Saeed Alazraqi1, Ibrahim Mohammed H Al Yami2, Azhar Ali Eassa Alanazyi2, Isra Abdullah Al Abdulmohsen2, Sakinah Mirza Al Karam2, Mwaed Abdulrazaq Ashri2, Zahra Hassan Alzayer2, Fahad Nayif Aldawood2, Hadeel Mohammed Alfiyadh2, Fahad Dakhel Dakheel Alahmadi3, Fahad Mabruk Naji Alraddadi3, Meshal Awad Alenazi3, Amal Diab O AlAmri4 and Kuthar Hassan Alzaher5

1King Abdulaziz University, Saudi Arabia
2Ministry of Health, Saudi Arabia
3Taibah University, Saudi Arabia
4King Khalid University, Saudi Arabia
5Vision College, Saudi Arabia
*Corresponding Author: Hisham Abbas Komo, Registered in Saudi Commission for Health Specialties as Saudi Board of OMFS and King Abdulaziz University, Saudi Arabia.
Received: October 25, 2021; Published: November 25, 2021


Introduction: Facial fractures with or without bone displacement are commonly seen in individuals with trauma. The treatment in such cases should consist of repositioning and immobilizing the fractured fragments to restore the function and cosmetic problems. Traditionally, titanium plates were used to immobilize the displaced segments and were considered the' gold standard. However, the recent introduction of bioresorbable plates as a substitute benefits from minimizing the need for the additional surgical procedure of removing the metal plate. Nevertheless, there remain ambiguities regarding the stability of resorbable fixations, the duration needed for their resorption, the risk of foreign body reactions, and some technical obstacles with resorbable plates.

Aim of Work: This review aims at highlighting an overview of the currently available bioresorbable materials and osteofixation systems for facial trauma.

Methodology: The review is a comprehensive research of PUBMED, Google Scholar, and WHO official page from 1966 to 2018.

Conclusion: Many developments have been made in bioresorbable plate systems using bioactive/resorbable osteoconductive materials. We present an overview of presently available resorbable implant materials and their uses in maxillofacial trauma, focusing on recent advancements.

Keywords: Bioresorbable Implants; Titanium Implants; Facial Fracture; Trauma; Bone Healing


  1. Dorri M., et al. “Resorbable versus titanium plates for facial fractures”. Cochrane Database of Systematic Reviews 1 (2009): CD007158.
  2. Kanno T., et al. “Overview of innovative advances in bioresorbable plate systems for oral and maxillofacial surgery”. Japanese Dental Science Review3 (2018): 127-138.
  3. Buijs GJ., et al. “A randomized clinical trial of biodegradable and titanium fixation systems in maxillofacial surgery”. Journal of Dental Research3 (2012): 299-304.
  4. Van Bakelen NB., et al. “Decision-making considerations in application of biodegradable fixation systems in maxillofacial surgery–a retrospective cohort study”. Journal of Cranio-Maxillofacial Surgery5 (2014): 417-422.
  5. Haers PE., et al. “Biodegradable polylactide plates and screws in orthognathic surgery”. Journal of Cranio-Maxillofacial Surgery2 (1998): 87-91.
  6. Ray MS., et al. “Metallic fragments on the surface of miniplates and screws before insertion”. British Journal of Oral and Maxillofacial Surgery1 (1999): 14-18.
  7. Erkmen E., et al. “Three-dimensional finite element analysis used to compare methods of fixation after sagittal split ramus osteotomy: setback surgery-posterior loading”. British Journal of Oral and Maxillofacial Surgery2 (2005): 97-104.
  8. Al-Moraissi E A and Ellis III E. “Biodegradable and titanium osteosynthesis provide similar stability for orthognathic surgery”. Journal of Oral and Maxillofacial Surgery9 (2015): 1795-1808.
  9. Sukegawa S., et al. “Clinical evaluation of an unsintered hydroxyapatite/poly-L-lactide osteoconductive composite device for the internal fixation of maxillofacial fractures”. The Journal of Craniofacial Surgery6 (2016): 1391.
  10. Schumann P., et al. “Perspectives on resorbable osteosynthesis materials in craniomaxillofacial surgery”. Pathobiology4 (2013): 211-217.
  11. Yang L., et al. “Complications of absorbable fixation in maxillofacial surgery: a meta-analysis”. PLoS One6 (2013): e67449.
  12. Siniscalchi EN., et al. “Titanium miniplates: a new risk factor for the development of the bisphosphonate-related osteonecrosis of the jaw”. The Journal of Craniofacial Surgery1 (2013): e1-e2.
  13. Leenslag JW., et al. “Resorbable materials of poly (L-lactide). VI. Plates and screws for internal fracture fixation”. Biomaterials1 (1987): 70-73.
  14. Vert M., et al. “New insights on the degradation of bioresorbable polymeric devices based on lactic and glycolic acids”. Clinical Materials1-2 (1992): 3-8.
  15. Kulkarni RK., et al. “Polylactic acid for surgical implants”. Archives of Surgery5 (1966): 839-843.
  16. Kulkarni RK., et al. “Biodegradable poly (lactic acid) polymers”. Journal of Biomedical Materials Research 3 (1971): 169-181.
  17. Cheung LK., et al. “A randomized controlled trial of resorbable versus titanium fixation for orthognathic surgery”. Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology4 (2004): 386-397.
  18. Park YW. “Bioabsorbable osteofixation for orthognathic surgery”. Maxillofacial Plastic and Reconstructive Surgery1 (2015): 1-9.
  19. Bali R K., et al. “To evaluate the efficacy of biodegradable plating system for fixation of maxillofacial fractures: A prospective study”. National Journal of Maxillofacial Surgery2 (2013): 167.
  20. Yolcu Ü., et al. “Cytotoxicity evaluation of bioresorbable fixation screws on human gingival fibroblasts and mouse osteoblasts by real-time cell analysis”. Journal of Oral and Maxillofacial Surgery8 (2015): 1562-e1-10.
  21. Kanno T., et al. “Feasibility of single folded unsintered hydroxyapatite particles/poly-L-lactide composite sheet in combined orbital floor and medial wall fracture reconstruction”. Journal of Hard Tissue Biology2 (2017): 237-244.
  22. Shikinami Y., et al. “Ultra-high-strength resorbable implants made from bioactive ceramic particles/polylactide composites”. Bioceramics2 (1996): 391.
  23. Shikinami Y., et al. “The complete process of bioresorption and bone replacement using devices made of forged composites of raw hydroxyapatite particles/poly l-lactide (Fu-HA/PLLA)”. Biomaterials27 (2005): 5542-5551.
  24. Park C H., et al. “Resorbable skeletal fixation systems for treating maxillofacial bone fractures”. Archives of Otolaryngology–Head and Neck Surgery2 (2011): 125-129.
  25. Dorri M., et al. “Resorbable versus titanium plates for facial fractures”. Cochrane Database of Systematic Reviews 1 (2009): CD007158.
Citation: Hisham Abbas Komo., et al. “Bioresorbable Fixation of Facial Trauma: An Overview”. EC Dental Science 20.12 (2021): 31-38.

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