Research Article
Volume 20 Issue 11 - 2021
Evaluation of Ph of a Novel Bioceramic Material for Use in Endodontic Practice: An In-Vitro Analysis
Harpreet Singh1* and Pavita Kataria2
1Dean, BJS Research Institute and Professor, Endodontics, BJS Dental College and Hospital, Ludhiana, India
2Senior Lecturer, Periodontology, BJS Dental College and Hospital, Ludhiana, India
*Corresponding Author: Harpreet Singh, Dean, BJS Research Institute and Professor, Endodontics, BJS Dental College and Hospital, Ludhiana, India.
Received: August 04, 2021; Published: October 25, 2021




Abstract

Introduction: Bioceramic materials have a come long way in terms of their potential role in critical tooth saving procedures, especially during endodontic management. The process of developing new materials with MTA like properties is still in progress in order to make materials which are clinically efficient but at the same time cost effective. One of the essential pre-requisites of these bioceramic materials is their ability to attain a highly alkaline pH after setting so that they can exhibit the osteogenic potential. The current study was carried out in these lines in order to evaluate the alkalinity of the newly introduced MTA in the Indian market in order to explore its osteogenic potential as the biological properties of MTA are attributed to its alkalinity.

Aim: To investigate the pH of a novel Bioceramic material, MTA (Maarc Dental, India) in order to validate its osteogenic potential.

Methodology: MTA Powder was mixed with its special liquid as per the manufacturer’s instructions, ensuring the complete dissolution of the powder particles. 20 polyethylene tubes measuring 3 mm in diameter and 2 mm in height were filled with freshly prepared material. The samples were sealed in tubes containing 10 ml of distilled water and stored at 37 degree celsius. The pH was measured after 3 hours, 24 hours and 48 hours using a calibrated pH meter.

Observations and Results: The maximum pH was observed to be 10.59 after 24 hours with a mean of 10.52. After 24 hours, a gradual fall in pH was observed in the samples.

Conclusion: Within the parameters set in this study, it was concluded that new MTA seems to be promising enough as it obtained a high alkaline pH after 24 hours of mixing. However, long term clinical evaluation in patients is required to support the laboratory findings.

Keywords: Alkalinity; Bioceramics; Endodontics; MTA; pH

References

  1. Tabassum S and Khan FR. “Failure of endodontic treatment: The usual suspects”. European Journal of Dentistry1 (2016): 144-147.
  2. LeGeros RZ. “Properties of osteoconductive biomaterials: calcium phosphates”. Clinical Orthopaedics and Related Research 395 (2002): 81-98.
  3. Tang Z., et al. “The material and biological characteristics of osteoinductive calcium phosphate ceramics”. Regenerative Biomaterials 1 (2018): 43-59.
  4. Rusin Zhao., et al. “Bone Grafts and Substitutes in Dentistry: A Review of Current Trends and Developments”. Molecule 26 (2021): 3007.
  5. Hernán Coaguila-Llerena., et al. “Physicochemical Properties of a Bioceramic Repair Material – BioMTA”. Brazilian Dental Journal5 (2020): 511-515.
  6. Kaur M., et al. “MTA versus Biodentine: Review of Literature with a Comparative Analysis”. Journal of Clinical and Diagnostic Research8 (2017): ZG01-ZG05.
  7. Youssef AR., et al. “Effects of mineral trioxide aggregate, calcium hydroxide, biodentine and Emdogain on osteogenesis, Odontogenesis, angiogenesis and cell viability of dental pulp stem cells”. BMC Oral Health 19 (2019): 133.
  8. Galal M., et al. “Solubility, pH change, and calcium ion release of low solubility endodontic mineral trioxide aggregate”. Bulletin of the National Research Centre 44 (2020): 42.
  9. Shekhar S., et al. “Comparative pH and calcium ion release in newer calcium silicate-based root canal sealers”. Endodontology 31 (2019): 29-33.
  10. Lee SJ., et al. “Sealing ability of a mineral trioxide aggregate for repair of lateral root perforations”. The Journal of Endodontics 19 (1993): 541-544.
  11. Torabinejad M and Chivian N. “Clinical applications of mineral trioxide aggregate”. The Journal of Endodontics 3 (1999): 197-205.
  12. Abedi HR and Ingle JI. “Mineral trioxide aggregate: a review of a new cement”. The Journal of the California Dental Association 12 (1995): 36-39.
  13. Howard W Roberts., et al. “Mineral trioxide aggregate material use in endodontic treatment: A review of the literature”. Dental Materials 24 (2008): 149-164.
  14. Singh H., et al. “Biodentin: A promising dentin substitute”. JBR Journal of Interdisciplinary Medicine and Dental Science 5 (2014): 1000140.
  15. Stella Maris de Freitas Lima., et al. “Improvement of reparative bioceramics in endodontics- A clinical review”. Biomedical Journal of Scientific and Technical Research 3 (2020): 18306-183010.
  16. Eliaz N and Metoki N. “Calcium Phosphate Bioceramics: A Review of Their History, Structure, Properties, Coating Technologies and Biomedical Applications”. Materials4 (2017): 334.
  17. Raghavendra SS., et al. “Bioceramics in endodontics - a review”. Journal of Istanbul University Faculty of Dentistry3-1 (2017): S128-S137.
  18. Amini Ghazvini S., et al. “Ion release and pH of a new endodontic cement, MTA and Portland cement”. The Iranian Endodontic Journal2 (2009): 74-78.
  19. Macwan C and Deshpande A. “Mineral Trioxide Aggregate (MTA) in dentistry: A review of literature”. International Journal of Oral Health and Medical Research 6 (2014): 71-74.
Citation: Harpreet Singh and Pavita Kataria. “Evaluation of Ph of a Novel Bioceramic Material for Use in Endodontic Practice: An In-Vitro Analysis”. EC Dental Science 20.11 (2021): 03-09.

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