Research Article
Volume 20 Issue 2 - 2021
Association between Diabetes Mellitus and Extraction of Root Filled Tooth: A Systematic Review
Abdulkader Abdulelah Abulhamayel1*, Osamah Mohammed Alhazmi2, Azhar Haeider AlJalooud3, Fahad Abdullah Althobaiti4, Hanin Ali Abotalib5, Rabiyah Mohammed Omar6, Reem Abbas Al-Hamoud7, Abdulaziz Turki Alsahli8, Sharifa Jafar Alkallaf7, Mohammed Hassan Muhanna9 and Amjad Hussain Aljumaiei10
1Department of Endodontics, Khulais General Hospital, Khulais, Saudi Arabia
2General Dentist, Ministry of Health, Jazan, Saudi Arabia
3College of Dentistry, Medical University of Warsaw, Warsaw, Poland
4General Dentist, Security Forces Hospital, Riyadh, Saudi Arabia
5College of Dentistry, Ibn Sina National College for Medical Studies, Jeddah, Saudi Arabia
6College of Dentistry, Alfarabi Colleges, Jeddah, Saudi Arabia
7General Dentist, Dr Zahra Al Ibrahim Dental Clinic, Jeddah, Saudi Arabia
8General Dentist, Ministry of Health, Medina, Saudi Arabia
9General Dentist, First Health Cluster, Eastern Province, Saudi Arabia
10College of Dentistry, Alfarabi Colleges, Riyadh, Saudi Arabia
*Corresponding Author: Abdulkader Abdulelah Abulhamayel, Department of Endodontics, Khulais General Hospital, Khulais, Saudi Arabia.
Received: January 12, 2020; Published: January 19, 2021


Objectives: Diabetes mellitus is one of the most prevalent diseases worldwide. It is associated with decreased quality of life, high infection rate, and decreased wound healing. This leads to many complications especially, for endodontics. That is why in this study, we will assess the effect of diabetes on the root canal therapy for the apical periodontitis.

Methods: Four databases were searched using specific search terms. We included assess the risk of failure of root canal therapy in diabetic patients and the prevalence of root canal therapy failure and different outcomes reported in diabetic patients. The studies were assessed for the quality of evidence using the NIH quality assessment tool before being included for the review.

Results: Six studies fulfilled our inclusion criteria and had passed the quality assessment to be included for the qualitative evidence synthesis. Based on these studies, diabetes mellitus had the worst outcome among other systemic diseases. Two studies assessed factors affecting the outcome and it was related to preoperative preparation and state of the necrotic teeth. However, it was not significantly correlated with the HBA1C level.

Conclusion: Diabetes did not cause the failure of the root canal treatment but caused delayed healing. Diabetes effect on the root canal therapy is dependent on many factors that need to be more assessed in more studies.

Keywords: Apical Periodontitis; Root Canal Therapy; Diabetes Mellitus; Endodontic Treatment; Endodontics


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Citation: Abdulkader Abdulelah Abulhamayel., et al. “Association between Diabetes Mellitus and Extraction of Root Filled Tooth: A Systematic Review”. EC Dental Science 20.2 (2021): 20-28.

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