Research Article
Volume 19 Issue 10 - 2020
Regenerative Endodontic Treatment in Clinical Practice: A Systematic Review
Hatem Faisal Bajnaid1*, Hussain Zaki Alabdulwahhab2, Abdulhadi Mohammed Albandar3, Khulud Nasser Alhmamey4, Rahaf Abdullah Manzalawi4, Nada Mohammed Fallatah5, Renad Khalid Alamoudi6, Reem Mohammed Alharbi6, Asuf Naif Alabdali7, Abdulmalik Ahmed Alburayk8 and Maryam Nabeel Nasser6
1Department of Endodontics, King Fahad Hospital, Jeddah, Saudi Arabia
2Primary Health Care, Ministry of Health, Ras Tanura, Saudi Arabia
3Primary Health Care, Ministry of Health, Hail, Saudi Arabia
4College of Dentistry, Batterjee Medical College, Jeddah, Saudi Arabia
5College of Dentistry, Alfarabi Colleges, Jeddah, Saudi Arabia
6College of Dentistry, Ibn Sina National College, Jeddah, Saudi Arabia
7General Dentist, FMC, Jeddah, Saudi Arabia
8College of Dentistry, Alfarabi Colleges, Riyadh, Saudi Arabia
*Corresponding Author: Hatem Faisal Bajnaid, Department of Endodontics, King Fahad Hospital, Jeddah, Saudi Arabia.
Received: August 12, 2020; Published: September 24, 2020




Abstract

Recently, regenerative endodontic treatment (RET) has been recognized as a ‘paradigm shift’ regarding the management of immature teeth associated with pulp necrosis. Various reports have suggested the use of RET as a first-line therapeutic option when dealing with immature teeth, particularly when the roots are not yet fully developed. For that, a systematic electronic database search was conducted for relevant studies published from inception and till 24th June 2020 in seven databases. Several position statements and clinical recommendations regarding the use of RET in clinical practice have been released by the European Society of Endodontology (ESE) and the American Association of Endodontists (AAS). Such treatment modalities depend upon the tissue engineering concept components, including stem cells, scaffolds, and signaling molecules. In clinical practice, this treatment approach involves the process of disinfection and commonly the introduction of a blood clot into the root canal space. There are three main therapeutic goals of RET. The first goal is the resolution of associated clinical signs and symptoms. The second goal is to establish further root maturation. The final goal is the restoration of neurogenesis. Up till this point, RET has been unable to reach a proven result regarding the real regeneration of pulp tissue and dentine space. From a histological aspect, healing is achieved with repair from tissues that are originated mainly from the periodontal and osseous tissues, including bone-like tissues and cementum, rather than odontoblasts and pulp tissues. We have conducted the current literature review to provide an overview of the clinical and biological aspects of regenerative endodontic treatment.

Keywords: Regenerative; Endodontic; Treatment; Pulp: RET

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Citation: Hatem Faisal Bajnaid., et al. “Regenerative Endodontic Treatment in Clinical Practice: A Systematic Review”. EC Dental Science 19.10 (2020): 95-106.

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