Review Article
Volume 19 Issue 8 - 2020
Pharmacological Interactions of Drugs Used in Odontology. Implications in Patients with Systemic Diseases
Claudio Viveros Amador1*, María Dolores Jiménez Farfán1, Juan Carlos Hernández Guerrero1, Adán Horacio Viveros Amador2, Cuauhtli X Serrato Zapata3 and Héctor Calvillo López3
1Laboratorio de Inmunología, División de Estudios de Posgrado e Investigación, Facultad de Odontología, Universidad Nacional Autónoma de México, Circuito de la Investigación Científica s/n, Ciudad Universitaria, Ciudad de México, CP, México
2Hospital de Alta Especialidad “Manuel Ávila Camacho” Instituto Mexicano del Seguro Social, Centro, Puebla, México
3Centro de Rehabilitación y Educación Especial Zapata CREE, Avenida de la Salud s/n, Palo Escrito, Emiliano Zapata, Morelos, CP, México
*Corresponding Author: Claudio Viveros Amador, Laboratorio de Inmunología, División de Estudios de Posgrado e Investigación, Facultad de Odontología, Universidad Nacional Autónoma de México. Circuito de la Investigación Científica s/n, Ciudad Universitaria, Ciudad de México, CP, México.
Received: June 26, 2020; Published: July 23, 2020


Due to the increase of systemic diseases worldwide, patients under pharmacotherapeutic regimens for the treatment of their illnesses could require dental care and the administration of additional medications. The main way for a dental professional to make an adequate diagnosis is through an exhaustive review of the clinical antecedents of the patient. A correct diagnosis and a complete clinical history of the patient, including the prescribed drugs, is of great relevance because errors will invariably lead to treatments that can aggravate the disease or resolve poorly the underlying health problem. For this reason, no procedures should be performed if the clinical antecedents of the patient and the exploration are incorrect or incoherent. On the other hand, the need to know the interactions of drugs that can occur in a patient under medical treatment, even for short terms, is to be pointed out, especially in the most susceptible patients, like the elderly or patients with cardiopathies. Management of pain and infection is common in dental treatments and the substances commonly used in the dental practice for their control are non-steroidal anti-inflammatory drugs (NSAIDs), antibiotics and local anesthetics that contain vasoconstrictors, capable of generating pharmacological interactions that can diminish the effect of the medical prescription, increase or exacerbate a biological response. Knowledge of the pharmacokinetic and pharmacodynamics drug interactions diminishes the risk of compromising the medical/dental treatment.

Keywords: Pharmacological Interactions; NSAIDs; Antibiotics; Local Anesthetics


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Citation: Claudio Viveros Amador., et al. “Pharmacological Interactions of Drugs Used in Odontology. Implications in Patients with Systemic Diseases”. EC Dental Science 19.8 (2020): 96-106.

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