Research Article
Volume 19 Issue 7 - 2020
Clinico-Biochemical Evaluation of CRP and Complete Blood Count in Chronic Periodontitis
Kamalkishor Mankar1 and Pranjali Bawankar2*
1Reader, Department of Periodontics and Implantology, VSPM Dental College and Research Centre, Nagpur, India
2Senior Lecturer, Department of Periodontics and Implantology, VSPM Dental College and Research Centre, Nagpur, India
*Corresponding Author: Pranjali Bawankar, Senior Lecturer, Department of Periodontics, VSPM Dental College and Research Centre, Nagpur, India.
Received: March 23, 2020; Published: June 02, 2020


Introduction: A strong association of chronic periodontal disease and cardiovascular disorders has been established. The interlink being chronic inflammation. Serum levels of CRP have been shown to be a strong predictor of the risk of cardiovascular events. The relation of anemia and chronic inflammatory diseases has been reported. In light of the above-mentioned facts the present study was formulated to evaluate serum levels of CRP, Hb% WBC count and RBC count in patients with chronic periodontitis.

Objective: To compare and correlate the serum levels of C-reactive protein and WBC, RBC, Hb% in patients with chronic periodontitis and healthy controls.

Material and Methods: A total of 120 patients equally divided into four groups depending upon the severity of chronic periodontitis (CP) were recruited for the study. The serum levels of C-reactive protein were assessed using Enzyme Linked Immunosorbant Assay. The complete blood count including WBC, RBC, Hb% was obtained using CBC cell counter.

Results: The serum CRP and WBC levels were found to be elevated in severe CP patients as compared to moderate and mild CP patients. The RBC count and Hb % was found to be lowered in severe CP as compared to other groups.

Conclusion: Within the limitations of the study it can be conclude that the serum CRP levels increases with the severity of periodontal disease The WBC count also was found to be increased in severe chronic periodontitis cases thereby suggesting active inflammation. Whereas the RBC count and Hb count significantly decreases with the severity of periodontitis thereby increasing risk of anemia.

Keywords: Chronic Periodontitis; Cardiovascular Diseases; Anemia; Inflammation; Periodontal Disease


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Citation: Kamalkishor Mankar and Pranjali Bawankar. “Clinico-Biochemical Evaluation of CRP and Complete Blood Count in Chronic Periodontitis”. EC Dental Science 19.7 (2020): 04-12.

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