Research Article
Volume 19 Issue 6 - 2020
Comparative Evaluation of Efficacy of Platelet Rich Fibrin, DFDBA and in Combination of Both in Healing of Periapical Defects-An In-vivo Study
Bhavana Vankayala1*, Lakshmi Shilpa Devagudi2 and Nikesh Reddy C3
1Assistant Professor, Department of Conservative Dentistry and Endodontics Government, Dental College and Hospital, Hyderabad, India
2NTR University of Health Sciences, Vijayawada, India
3Rajiv Gandhi University of Health Sciences, Karnataka, India
*Corresponding Author: Bhavana Vankayala, Assistant Professor, Department of Conservative Dentistry and Endodontics, Government Dental College and Hospital, Hyderabad, Telangana, India.
Received: March 30, 2020; Published: May 05, 2020


Introduction: The main objective of this study is to evaluate the efficacy of PRF, DFDBA and combination of both in periapical defects healing.

Materials and Methods: 24 patients, aged between 20 - 40 years, were screened for bilateral periapical lesions of maxillary lesions below 2 cm in dimension in the radiograph and were included in the study. The patients were divided into 3 Groups with 8 in each, group 1: One lesion taken as control, another lesion treated with PRF, group 2: One lesion taken as control, another lesion treated with DFDBA, group 3: One lesion taken as control another lesion treated with combination of DFDBA and PRF. Patients recalled after 3 months and 6 months for clinical and radiographic evaluation followed by Morphometric area analysis (MA).

Results: On comparing percentage in bone formation from baseline to 6 months in Test vs Control showed more percentage change with Group 3 test containing both PRF and DFDBA.

Conclusion: Group III containing combination of PRF and DFDBA showed better results than other two groups containing PRF and DFDBA individually, but further long-term follow up as well as histological nature of newly formed tissues by either treatment remains to be elucidated.

Keyword: Platelet Rich Fibrin; DFDBA; Peri-radicular Surgery; Regenerative Endodontics


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Citation: Bhavana Vankayala., et al. “Comparative Evaluation of Efficacy of Platelet Rich Fibrin, DFDBA and in Combination of Both in Healing of Periapical Defects-An In-vivo Study”. EC Dental Science 19.6 (2020): 02-08.

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