Case Report
Volume 19 Issue 5 - 2020
Oral Limited Pemphigus Vulgaris-A Case Report
Maryam Jalili Sadrabad1 and Azra Mohiti2*
1Assistant Professor, Oral Medicine Department, Dental School, Semnan University of Medical Science, Semnan, Iran
2Assistant Professor, Oral Medicine Department, Dental School, Shahid Sadoughi University of Medical Science, Yazd, Iran
*Corresponding Author: Azra Mohiti, Assistant Professor, Oral Medicine Department, Dental School, Shahid Sadoughi University of Medical Science, Yazd, Iran.
Received: March 02, 2020; Published: April 14, 2020


Background: Pemphigus vulgaris (PV) is a chronic inflammatory mucocutaneous disease that occurs mostly in the 5 - 6 decade of life and Ashkenazi Jews racial groups. In most cases the disease begins with oral lesions and progresses to other mucosa and skin. Diagnosis of PV includes histopathologic examination of the affected area and confirmation with direct immunofluorescence test (DIF). Now days pemphigus Vulgaris is treated with corticosteroids in combination to other immune suppressor drugs, although consumption of them for long periods of time has its own challenging side effects.

Case Presentation: The patient was a 20-year-old woman who referred to the Oral Medicine Department of Semnan University of Medical Sciences by a dermatologist. Intraoral examinations revealed widespread wound throughout the mouth. The histopathologic report indicates Pemphigus Vulgaris. The patient was instructed to take oral corticosteroid. One month later, the dose of the drug was tapered and no recurrence was observed at the constant maintenance dose for 4 months.

Discussion and Conclusion: As stated PV is an autoimmune disease which are is common in middle age but this patient was only 20 years old which is an uncommon age for PV. It can be debated that in the modern era because of higher stress levels in the society especially women, the incidence of stress related diseases could increase and also the occurrence age could decrease significantly as seen in this case. In our case because there was only oral cavity involvement is seen, low dose of corticosteroids was initiated as treatment in despite of standard high doses. This report showed that low doses of corticosteroids could be used in cases of isolated PV in the oral cavity.

Keywords: Pemphigus Vulgaris; Oral Medicine; Stress


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Citation: Maryam Jalili Sadrabad and Azra Mohiti. “Oral Limited Pemphigus Vulgaris-A Case Report”. EC Dental Science 19.5 (2020): 70-75.

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