Case Report
Volume 19 Issue 5 - 2020
Treatment of Periodontal Intrabony Defect Using Autologous Periodontal Ligament Stem Cells: A Case Report of 2 Years Follow-Up and Surgical Re-Entry
Shalini HS1 and Vandana KL2*
1Senior Lecturer, Yogita Dental College and Hospital, Naringi Riverside, Khed, Maharashtra, India
2Senior Professor, Former Associate Dean of Academics, Department of Periodontics, College of Dental Sciences, Davangere, Karnataka, India
*Corresponding Author: Vandana KL, Senior Professor, Former Associate Dean of Academics, Department of Periodontics, College of Dental Sciences, Davangere, Karnataka, India.
Received: January 09, 2020; Published: April 14, 2020


Periodontists have been interested in regenerating tooth-supporting tissues destroyed by periodontal diseases. Currently regeneration of periodontal damaged tissue still remains great challenge. Stem cell-based therapy raised novel therapeutic strategies for periodontal regeneration. To date, substantial advances have been made in stem cell-based periodontal regeneration with autologous periodontal ligament stem cell niche. Currently there is dearth of evidence regarding the success of this therapy, especially evidence for the effectiveness of autologous periodontal ligament stem cells. We present a case report of a 38-year-old male patient having periodontal osseous defect w.r.t 36 was treated with autologous periodontal ligament stem cell niche harvested from third molar. Surgical re-entry at 2 years revealed bone formation w.r.t 36. At one year, 75% radiographic bone gain was accomplished. The improvement in the clinical and radiographic parameters reinforced by the re-entry surgery findings strongly suggest that A-PDLSCs Niche may be a cost-effective substitute to implants and tooth supported prosthesis in situations where conventional periodontal therapy would yield compromised outcomes.

Keywords: Intrabony Defect; Autologous; Periodontal Ligament Stem Cells; Surgical Re-Entry; Regeneration


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Citation: Shalini HS and Vandana KL. “Treatment of Periodontal Intrabony Defect Using Autologous Periodontal Ligament Stem Cells: A Case Report of 2 Years Follow-Up and Surgical Re-Entry”. EC Dental Science 19.5 (2020): 61-69.

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