Research Article
Volume 19 Issue 3 - 2020
Masticatory Deficiency and Deficit of Cognitive Function, Attention, Learning and Memory
Jeanne José Iwayama1*, Carina Pereira Leite Esperancinha1 and Patrícia Valério2
1Dentist, Researcher at Wilma Simões European Institute, Lisbon
2Pos Doc Researcher at Federal University of Minas Gerais, Brazil
*Corresponding Author: Jeanne José Iwayama, Dentist, Researcher at Wilma Simões European Institute, Lisbon.
Received: February 07, 2020; Published: February 28, 2020


Numerous animal and human evidence to date demonstrates the Masticatory Act as an entity not only responsible for the grinding and processing of nutritious food, but as a complex and refined system of recognition and transmission of stimuli to the Central Nervous System (CNS) through multiple sensory inputs and a complex communication network between the brain and the stomatognathic system currently defined as the brain-stomatognathic axis.

Mastication triggers metabolic processes responsible for maintaining not only the physical health, but mainly for the intellectual preservation of the individual and it is closely linked to the cognitive function.

As well as, masticatory deficiency resulting from occlusal disharmony, soft food diet or the absence of teeth, as a chronic stress agent that activates the hypothalamus-pituitary-adrenal axis (HPA) and increased circulating glucocorticoids as a promoter of various pathologies.

In this work, we make a brief integrative review including radiological exams, serological and behavioral analysis of the past 20 years in animals and humans with clear influence of masticatory dysfunction on hippocampal-dependent cognitive decline. The review includes recent longitudinal cohort studies of tooth loss and cognitive decline in humans.

Keywords: Chewing; Mastication; Brain Activity; Cognitive Function; Chewing and Dementia


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Citation: Jeanne José Iwayama., et al. “Masticatory Deficiency and Deficit of Cognitive Function, Attention, Learning and Memory”. EC Dental Science 19.3 (2020): 01-15.

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