Research Article
Volume 7 Issue 1 - 2020
Comparison between PCI in Anterior ST-Elevation Myocardial Infarction and Equivalents in Gaza (PCI-STEMI)
Mohammed Habib*
Cardiology Department, Alshifa Hospital, Gaza, Palestine
*Corresponding Author: Mohammed Habib, Cardiology Department, Alshifa Hospital, Gaza, Palestine.
Received: December 05, 2019; Published: December 12, 2019


Background: A primary percutaneous coronary (PCI) intervention and pharmaco-invasive (PCI) continues to be the optimal reperfusion therapy in patients with anterior ST elevation myocardial infarction (STEMI) however, the optimal treatment in patients with anterior STEMI equivalents (wellness and De Winter syndromes) is unknown.

Methods: Patients presenting within 2 hours of symptom onset, divided according to electrocardiography (ECG) into two groups, the first group: acute anterior STEMI treated by primary PCI < 2 hours or pharmaco-invasive PCI 2 - 24 hours after streptokinase, and second group: acute anterior STEMI equivalents (wellness and De Winter syndromes) treated with early PCI < 24 hours. The primary (efficacy) endpoint a composite of death, shock and congestive heart failure at 30 days after hospitalization.

Results: Total 173 patients (134 patients: anterior STEMI, 39 patients: Anterior STEMI Equivalents) with mean age 56.2 ± 9.4 years, the mean age was 55.1 ± 9.2 years for the Anterior STEMI group, and 59.7 ± 9.1 years in Anterior STEMI equivalents group. (P:0.007). The female gender was higher in Anterior STEMI Equivalents compared with anterior STEMI (P: 0.036). Efficacy (primary) endpoint: total death, shock or heart failure at 30 days after hospitalization was seen in myocardial infarction was significantly higher in patient with anterior STEMI group compared with anterior STEMI equivalent group (P:0.011). the total death, shock and heart failure were significant in anterior STEMI group (P: 0.047, 0.024 and 0.028) respectively.

Conclusion: A strategy of early PCI less than 24 hours in patients with Anterior STEMI Equivalents has safe and less adverse events than anterior STEMI with primary PCI < 2 hours and/or pharmaco-invasive PCI 2-24 hours after streptokinase administration.

Keywords: Percutaneous Coronary (PCI); ST Elevation Myocardial Infarction (STEMI)


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Citation: Mohammed Habib., et al. “Comparison between PCI in Anterior ST-Elevation Myocardial Infarction and Equivalents in Gaza (PCI-STEMI)”. EC Cardiology 7.1 (2020): 01-08.

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