Research Article
Volume 7 Issue 2 - 2020
A Drug Review of Trimetazidine on its Role as Add-On Therapy in Stable Angina
Vikram Rajasekar1*, Ravish Katira2
1Foundation Doctor, St. Helens and Knowsley Teaching Hospitals NHS Trust, UK
2Consultant Cardiologist, St. Helens and Knowsley Teaching Hospitals NHS Trust, UK
*Corresponding Author: Vikram Rajasekar, Foundation Doctor, St. Helens and Knowsley Teaching Hospitals NHS Trust, UK.
Received: December 17, 2019; Published: January 10, 2020


Ischaemic heart disease is a very common condition affecting many. Those with stable angina are generally treated with agents such nitrates, calcium channel and beta blockers; haemodynamic agents that affect blood pressure. This review explores the futility of trimetazidine, a non-haemodynamic agent, in patients with chronic stable angina. Out of the eight articles reviewed, evidence suggests that trimetazidine can play a role as add-on to the current class of antianginals. Trials show that using trimetazidine as an add-on therapy to beta-blockers and/or calcium channel blockers significantly reduces the frequency and severity of angina pectoris and the associated usage of short acting nitrates. The overall tolerability of the drug seems favourable for usage in those with stable angina pectoris.

Keywords: Drug; Trimetazidine; Stable Angina


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Citation: Vikram Rajasekar and Ravish Katira. “A Drug Review of Trimetazidine on its Role as Add-On Therapy in Stable Angina”. EC Cardiology 7.2 (2020): 01-09.

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