Review Article
Volume 9 Issue 5 - 2022
Challenges for the Generation of Real-World Evidence in Heart Failure in Europe
Vera Vesela*, Shashidhar Rao and Rachel Studer
Novartis Pharma AG, Basel, Switzerland
*Corresponding Author: Vera Vesela, Novartis Pharma AG, Basel, Switzerland.
Received: June 26, 2022; Published: June 28, 2022


Heart failure (HF) constitutes a substantial health burden in Europe and, indeed, globally, warranting improvements in disease management strategies. Real-world evidence (RWE) research is a useful tool that can guide treatment intervention and preventative strategies if based on large, comprehensive data sources, covering a wide variety of patient demographics and clinical characteristics. However, some inherent challenges associated with HF that influence the generation of RWE in Europe are those relating to diagnosis and disease management. Despite the availability of evidence-based guidelines for HF treatment, heterogeneity in the HF population and disease course can contribute to variation in the management of HF in routine clinical practice globally, making interpretation of real-world data difficult. In this review, we summarise and discuss these challenges in the context of ways in which they affect the generation of RWE in HF. Addressing these matters could see greatly increased usability of RWE in HF, which could translate into improvement in treatment interventions and best practice of patient care.

Keywords: Real-World Evidence; Heart Failure; Europe; Disease Management; Registry


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Citation: Vera Vesela., et al. “Challenges for the Generation of Real-World Evidence in Heart Failure in Europe”. EC Cardiology 9.5 (2022): 03-12.

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