Review Article
Volume 9 Issue 3 - 2022
The Beneficial Effects of Honey on the Human Heart, Cardiovascular System, and Non-Cardio Conditions
Uzoamaka Nwokorie1, Nicholas A Kerna2,3*, Sudeep Chawla4, ND Victor Carsrud5, Obiamaka Pamela Okereke6, Hilary M Holets7,8, Chinwendu Olivia Ayozie9, Victor P Nkwopara10, Stephen M Brown11 and Chizoba Martin Ani12

1University of Washington, USA

2SMC-Medical Research, Thailand

3First Inter Health Group, Thailand

4Chawla Health and Research, USA

5Lakeline Wellness Center, USA

6Life is Beautiful, USA

7Beverly Hills Wellness Surgical Institute, USA

8Orange Partners Surgicenter, USA

9Madonna University College of Medicine, Nigeria

10Olusanya Rufai Medical Center, USA

11International University of Health Sciences, St. Kitts

12Ave Maria Hospital, Nigeria

*Corresponding Author: Nicholas A Kerna, (mailing address) POB47 Phatphong, Suriwongse Road, Bangkok, Thailand 10500. Contact:
Received: April 18, 2022; Published: April 26, 2022


Honey is produced all over the world and contains small amounts of sugars, enzymes, amino acids, minerals, trace elements, vitamins, scent molecules, and polyphones. All generations and civilizations, ancient and modern, recognize it as food and medicine. Honey has been consumed in various ways, including a sugar substitute and flavoring ingredient. Carbohydrates, such as monosaccharides, fructose, and glucose, are the essential elements in honey. Honey has a plethora of additional compounds at minuscule levels that have antiviral, antiparasitic, anticancer, anti-inflammatory, antimutagenic, antioxidant, immunosuppressive, and antibacterial properties. It can also be used as an antidiabetic and weight management supplement. Alongside its therapeutic properties, it also functions as a prebiotic, promoting the development of probiotic bacteria. Honey’s importance has been recognized in scientific papers, and there is compelling evidence to support its therapeutic use. This review aims to present the history of honey and investigate its role in medicine and cosmetics.

Keywords: Amino Acids; Antibacterial Properties; Immunosuppressant; Natural Cardiovascular Cures; Natural Diabetes Treatment; Trace Elements; Weight Management


  1. Allsop KA and Miller JB. “Honey revisited: a reappraisal of honey in pre-industrial diets”. British Journal of Nutrition 4 (1996): 513-520.
  2. Eteraf-Oskouei T and Najafi M. “Traditional and modern uses of natural honey in human diseases: a review”. Iranian Journal of Basic Medical Sciences 6 (2013): 731-742.
  3. Samarghandian S., et al. “Honey and health: A review of recent clinical research”. Pharmacognosy Research 2 (2017): 121-127.
  4. Nayik GA., et al. “Honey: its history and religious significance: a review”. Universal Journal of Pharmacy01 (2014): 5-8.
  5. Arawwawala M and Hewageegana S. “Health benefits and traditional uses of honey: A review”. Journal of Apitherapy1 (2017): 9.
  6. Ediriweera ERHSS and Premarathna NYS. “Medicinal and cosmetic uses of Bee’s Honey - A review”. Ayu2 (2012): 178-182.
  7. Jones R. “Prologue: Honey and healing through the ages”. Journal of ApiProduct and ApiMedical Science1 (2009): 2-5.
  8. Purbafrani A., et al. “The benefits of honey in the Holy Quran”. International Journal of Pediatrics3 (2014): 67-73.
  9. Rena Goldman CC. “Raw honey benefits and risks: Healing, topical use, immune boost”. Healthline (2022).
  10. Subramanian R., et al. “Processing of honey: A review”. International Journal of Food Properties1 (2007): 127-143.
  11. Bogdanov S. Honey types (2022).
  12. Definition of honey and honey products (2022).
  13. Sharma B., et al. “Utilization of honey for functional food product development”. Actascientific (2020).
  14. Honey-based formulations and drug purposes. In: Honey in Traditional and Modern Medicine. CRC Press (2013): 295-348.
  15. Marar A. “A sweet success story: In 12 years, India’s honey production grows by 200%, exports by 207%”. The Indian Express (2022).
  16. Umesh Hebbar H., et al. “Properties of dried and intermediate moisture honey products: A review”. International Journal of Food Properties 4 (2008): 804-819.
  17. Sharma B., et al. “Utilization of honey for functional food product development”. Actascientific (2022).
  18. Bellik Y and Iguerouada M. Honey in Food Industry (2022).
  19. Bobiş O., et al. “Honey and diabetes: The importance of natural, simple sugars in the diet for preventing and treating different types of diabetes”. Oxid Med Cell Longev (2018): 1-12.
  20. Nordqvist C. “Added sugar: What you need to know”. Medicalnewstoday (2017).
  21. Honey vs. sugar. Diffen (2022).
  22. Johnson T. “Is honey nutritious? - nature Nate’s”. Nature Nate’s (2019).
  23. Mohan A., et al. “Effect of honey in improving the gut microbial balance”. Food Quality and Safety 2 (2017): 107-115.
  24. Martinez-Armenta C., et al. “Therapeutic potential of bioactive compounds in honey for treating osteoarthritis”. Frontiers in Pharmacology 12 (2021): 642836.
  25. Meo SA., et al. “Role of honey in modern medicine”. Saudi Journal of Biological Sciences 5 (2017): 975-978.
  26. Alvarez-Suarez JM., et al. “Contribution of honey in nutrition and human health: a review”. The Mediterranean Journal of Nutrition and Metabolism 1 (2010): 15-23.
  27. Gebru YG., et al. “Review on honeybee's role in climate change mitigation and poverty alleviation”. Livestock Research for Rural Development (2016): 28.
  28. Millar H. “Why bees are so important to human life and health”. Medicalnewstoday (2021).
  29. Kouchner C., et al. “Bee farming system sustainability: An assessment framework in metropolitan France”. Agricultural Systems 102653 (2019): 102653.
  30. In A. “Honey Bee Farming Project Report, cost, profits”. Agri Farming (2018).
  31. In A. “Sugarcane Farming Project Report, Cost and Profit”. Agri Farming (2018).
  32. Omidi-Arjenaki O., et al. “Analysis of energy input and output for honey production in Iran (2012–2013)”. Renewable and Sustainable Energy Reviews 59 (2016): 952-957.
  33. Uddin MT., et al. “Value chain analysis of honey in Bangladesh: Production practices and livelihood perspective”. SAARC Journal of Agriculture 2 (2022): 301-315.
  34. Kumar TE., et al. “Cost and Returns of Sugarcane Production at Different Size Groups of Farms in District Meerut (UP)”. India Annals of Agri-Bio Research 3 (2014): 561-565.
  35. Al-Waili N., et al. “Antibiotic, pesticide, and microbial contaminants of honey: human health hazards”. Scientific World Journal (2012): 930849.
  36. Bogdanov S. “Contaminants of bee products”. Apidologie 1 (2006): 1-18.
  37. Moynihan P. “Sugars and dental caries: Evidence for setting a recommended threshold for intake”. Advances in Nutrition 1 (2016): 149-156.
  38. Arora S. “FSSAI operationalises the revised standards for honey”. Food Safety Helpline (2022).
  39. Nataliya L., et al. “Natural Honey Market”. The International Science 4 (2020): 43-56.
  40. Wahab A., et al. “Long-term effects of honey on cardiovascular parameters and anthropometric measurements of postmenopausal women”. Complementary Therapies in Medicine 41 (2018): 154-160.
  41. Farooqui T and A Farooqui A. “Health benefits of honey: Implications for treating cardiovascular diseases”. Current Nutrition and Food Science 4 (2011): 232-252.
  42. Zhang S., et al. “Associations between honey consumption and prehypertension in adults aged 40 years and older”. Clinical and Experimental Hypertension 5 (2020): 420-427.
  43. Khalil MI., et al. “Cardioprotective effects of Tualang honey: Melioration of cholesterol and cardiac enzymes levels”. BioMed Research International (2015): 1-8.
  44. Ahmad A., et al. “Anti-inflammatory effect of natural honey on bovine thrombin-induced oxidative burst in phagocytes”. Phytotherapy Research 6 (2009): 801-808.
  45. Yaghoobi N., et al. “Natural honey and cardiovascular risk factors; effects on blood glucose, cholesterol, triacylglycerole, CRP, and body weight compared with sucrose”. Scientific World Journal 8 (2008): 463-469.
  46. Najafi M., et al. “Effects of chronic oral administration of natural honey on ischemia/reperfusion-induced arrhythmias in isolated rat heart”. Iranian Journal of Basic Medical Sciences 14 (2011): 75-81.
  47. BBC News. “Curious reaction to honey “can cause heart arrhythmia”. BBC News (2022).
Citation: Nwokorie U, Kerna NA, Chawla S, Carsrud NDV, Okereke OP, Holets HM, Ayozie CO, Nkwopara VP, Brown SM, Ani CM. “The Beneficial Effects of Honey on the Human Heart, Cardiovascular System, and Non-Cardio Conditions”. EC Cardiology 9.3 (2022): 13-26.

PubMed Indexed Article

EC Pharmacology and Toxicology
LC-UV-MS and MS/MS Characterize Glutathione Reactivity with Different Isomers (2,2' and 2,4' vs. 4,4') of Methylene Diphenyl-Diisocyanate.

PMID: 31143884 [PubMed]

PMCID: PMC6536005

EC Pharmacology and Toxicology
Alzheimer's Pathogenesis, Metal-Mediated Redox Stress, and Potential Nanotheranostics.

PMID: 31565701 [PubMed]

PMCID: PMC6764777

EC Neurology
Differences in Rate of Cognitive Decline and Caregiver Burden between Alzheimer's Disease and Vascular Dementia: a Retrospective Study.

PMID: 27747317 [PubMed]

PMCID: PMC5065347

EC Pharmacology and Toxicology
Will Blockchain Technology Transform Healthcare and Biomedical Sciences?

PMID: 31460519 [PubMed]

PMCID: PMC6711478

EC Pharmacology and Toxicology
Is it a Prime Time for AI-powered Virtual Drug Screening?

PMID: 30215059 [PubMed]

PMCID: PMC6133253

EC Psychology and Psychiatry
Analysis of Evidence for the Combination of Pro-dopamine Regulator (KB220PAM) and Naltrexone to Prevent Opioid Use Disorder Relapse.

PMID: 30417173 [PubMed]

PMCID: PMC6226033

EC Anaesthesia
Arrest Under Anesthesia - What was the Culprit? A Case Report.

PMID: 30264037 [PubMed]

PMCID: PMC6155992

EC Orthopaedics
Distraction Implantation. A New Technique in Total Joint Arthroplasty and Direct Skeletal Attachment.

PMID: 30198026 [PubMed]

PMCID: PMC6124505

EC Pulmonology and Respiratory Medicine
Prevalence and factors associated with self-reported chronic obstructive pulmonary disease among adults aged 40-79: the National Health and Nutrition Examination Survey (NHANES) 2007-2012.

PMID: 30294723 [PubMed]

PMCID: PMC6169793

EC Dental Science
Important Dental Fiber-Reinforced Composite Molding Compound Breakthroughs

PMID: 29285526 [PubMed]

PMCID: PMC5743211

EC Microbiology
Prevalence of Intestinal Parasites Among HIV Infected and HIV Uninfected Patients Treated at the 1o De Maio Health Centre in Maputo, Mozambique

PMID: 29911204 [PubMed]

PMCID: PMC5999047

EC Microbiology
Macrophages and the Viral Dissemination Super Highway

PMID: 26949751 [PubMed]

PMCID: PMC4774560

EC Microbiology
The Microbiome, Antibiotics, and Health of the Pediatric Population.

PMID: 27390782 [PubMed]

PMCID: PMC4933318

EC Microbiology
Reactive Oxygen Species in HIV Infection

PMID: 28580453 [PubMed]

PMCID: PMC5450819

EC Microbiology
A Review of the CD4 T Cell Contribution to Lung Infection, Inflammation and Repair with a Focus on Wheeze and Asthma in the Pediatric Population

PMID: 26280024 [PubMed]

PMCID: PMC4533840

EC Neurology
Identifying Key Symptoms Differentiating Myalgic Encephalomyelitis and Chronic Fatigue Syndrome from Multiple Sclerosis

PMID: 28066845 [PubMed]

PMCID: PMC5214344

EC Pharmacology and Toxicology
Paradigm Shift is the Normal State of Pharmacology

PMID: 28936490 [PubMed]

PMCID: PMC5604476

EC Neurology
Examining those Meeting IOM Criteria Versus IOM Plus Fibromyalgia

PMID: 28713879 [PubMed]

PMCID: PMC5510658

EC Neurology
Unilateral Frontosphenoid Craniosynostosis: Case Report and a Review of the Literature

PMID: 28133641 [PubMed]

PMCID: PMC5267489

EC Ophthalmology
OCT-Angiography for Non-Invasive Monitoring of Neuronal and Vascular Structure in Mouse Retina: Implication for Characterization of Retinal Neurovascular Coupling

PMID: 29333536 [PubMed]

PMCID: PMC5766278

EC Neurology
Longer Duration of Downslope Treadmill Walking Induces Depression of H-Reflexes Measured during Standing and Walking.

PMID: 31032493 [PubMed]

PMCID: PMC6483108

EC Microbiology
Onchocerciasis in Mozambique: An Unknown Condition for Health Professionals.

PMID: 30957099 [PubMed]

PMCID: PMC6448571

EC Nutrition
Food Insecurity among Households with and without Podoconiosis in East and West Gojjam, Ethiopia.

PMID: 30101228 [PubMed]

PMCID: PMC6086333

EC Ophthalmology
REVIEW. +2 to +3 D. Reading Glasses to Prevent Myopia.

PMID: 31080964 [PubMed]

PMCID: PMC6508883

EC Gynaecology
Biomechanical Mapping of the Female Pelvic Floor: Uterine Prolapse Versus Normal Conditions.

PMID: 31093608 [PubMed]

PMCID: PMC6513001

EC Dental Science
Fiber-Reinforced Composites: A Breakthrough in Practical Clinical Applications with Advanced Wear Resistance for Dental Materials.

PMID: 31552397 [PubMed]

PMCID: PMC6758937

EC Microbiology
Neurocysticercosis in Child Bearing Women: An Overlooked Condition in Mozambique and a Potentially Missed Diagnosis in Women Presenting with Eclampsia.

PMID: 31681909 [PubMed]

PMCID: PMC6824723

EC Microbiology
Molecular Detection of Leptospira spp. in Rodents Trapped in the Mozambique Island City, Nampula Province, Mozambique.

PMID: 31681910 [PubMed]

PMCID: PMC6824726

EC Neurology
Endoplasmic Reticulum-Mitochondrial Cross-Talk in Neurodegenerative and Eye Diseases.

PMID: 31528859 [PubMed]

PMCID: PMC6746603

EC Psychology and Psychiatry
Can Chronic Consumption of Caffeine by Increasing D2/D3 Receptors Offer Benefit to Carriers of the DRD2 A1 Allele in Cocaine Abuse?

PMID: 31276119 [PubMed]

PMCID: PMC6604646

EC Anaesthesia
Real Time Locating Systems and sustainability of Perioperative Efficiency of Anesthesiologists.

PMID: 31406965 [PubMed]

PMCID: PMC6690616

EC Pharmacology and Toxicology
A Pilot STEM Curriculum Designed to Teach High School Students Concepts in Biochemical Engineering and Pharmacology.

PMID: 31517314 [PubMed]

PMCID: PMC6741290

EC Pharmacology and Toxicology
Toxic Mechanisms Underlying Motor Activity Changes Induced by a Mixture of Lead, Arsenic and Manganese.

PMID: 31633124 [PubMed]

PMCID: PMC6800226

EC Neurology
Research Volunteers' Attitudes Toward Chronic Fatigue Syndrome and Myalgic Encephalomyelitis.

PMID: 29662969 [PubMed]

PMCID: PMC5898812

EC Pharmacology and Toxicology
Hyperbaric Oxygen Therapy for Alzheimer's Disease.

PMID: 30215058 [PubMed]

PMCID: PMC6133268

News and Events

November Issue Release

We always feel pleasure to share our updates with you all. Here, notifying you that we have successfully released the November issue of respective journals and the latest articles can be viewed on the current issue pages.

Submission Deadline for Upcoming Issue

ECronicon delightfully welcomes all the authors around the globe for effective collaboration with an article submission for the upcoming issue of respective journals. Submissions are accepted on/before December 14, 2022.

Certificate of Publication

ECronicon honors with a "Publication Certificate" to the corresponding author by including the names of co-authors as a token of appreciation for publishing the work with our respective journals.

Best Article of the Issue

Editors of respective journals will always be very much interested in electing one Best Article after each issue release. The authors of the selected article will be honored with a "Best Article of the Issue" certificate.

Certifying for Review

ECronicon certifies the Editors for their first review done towards the assigned article of the respective journals.

Latest Articles

The latest articles will be updated immediately on the articles in press page of the respective journals.