Review Article
Volume 8 Issue 11 - 2021
Diabetic Related Cardiomyopathy, Pathophysiology, Diagnosis and Potential Treatments
Hanan B Albackr*
Associate Professor of Medicine, Cardiology Consultant, King Fahad Cardiac Center, King Khalid University Hospital, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia
*Corresponding Author: Hanan B Albackr, Associate Professor of Medicine, Cardiology Consultant, King Fahad Cardiac Center, King Khalid University Hospital, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia.
Received: September 23, 2021; Published: October 29, 2021




Abstract

Patients with diabetes mellitus are at increased risk of heart failure irrespective of presence of other heart failure causes like CAD or hypertension. This cardiomyopathy is called diabetic cardiomyopathy (DCM), the detection of which is challenging since most of diabetic patients have other risk factors for developing heart failure. The exact causing pathological mechanism of DCM is unknown but possible mechanisms are related mainly to hyperglycemia leading to many changes like increase free fatty acids, microvascular disease, cellular fibrosis and apoptosis. There is no specific treatment to patients with heart failure related to DMC. Currently there are new medical treatment for type II DM like GLP-1 receptor agonists (GLP-1RA) and Sodium-glucose transporter type 2 (SGLT2) inhibitors that has been shown to decrease the risk of atherosclerotic cardiac diseases in diabetic patients and subsequently heart failure.

Keywords: Diabetes Mellitus; Cardiomyopathy; Pathophysiology

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Citation: Hanan B Albackr. “Diabetic Related Cardiomyopathy, Pathophysiology, Diagnosis and Potential Treatments”. EC Cardiology 8.11 (2021): 18-29.

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