Research Article
Volume 8 Issue 9 - 2021
Global Longitudinal Strain and Echocardiographic Parameters of Left Ventricular Geometry and Systolic Function in Healthy Adult Angolans: Effect of Age and Gender. A Pilot Study
Humberto Morais1*, Ana Feijão2 and Savarino de Victória Pereira3
1Department of Cardiology, Hospital Militar Principal/Instituto Superior, Luanda, Angola
2Department of Cardiology, Luanda Medical Center, Luanda, Angola
3Service of Cardiology, Hospital Américo Boavida, Angola
*Corresponding Author: Humberto Morais, Department of Cardiology, Hospital Militar Principal/Instituto Superior, Luanda, Angola.
Received: July 23, 2021; Published: August 30, 2021


Introduction: Studies on the normal echocardiographic reference values in Africans are limited. 

Objectives: This study aims to establish the normal left ventricular echocardiographic parameters for adult Angolans, stratified by gender and age. 

Methods: A cross-sectional study was performed involving healthy adults attending a diagnostic center in Luanda, Angola. The two-dimensional transthoracic echocardiography was performed according to the Guidelines of the American Society of Echocardiography and the European Association of Cardiovascular Imaging. 

Results: A total of 103 men (47.5%) (mean age: 39,5 ± 10,8) and 114 women (52,5%) (mean age: 43,0 ± 12,5 years) were included. Compared to men, women were older (p = 0,025) and showed significantly smaller body surface area (BSA) (p < 0,001). Left ventricular wall thickness, left ventricular end-diastolic dimension and volume (LVEDV), left ventricular mass (LVM) and LVM indexed to BSA (LVMi) were significantly lower in women (p < 0.005). While LVEDD indexed to BSA and left ventricular ejection fraction (LVEF) was significantly higher in women compared to men (p = 0,007), (p = 0,01), respectively. Mitral annular plane systolic excursion, LVEF by strain, and the global longitudinal strain showed no gender differences. Posterior wall thickness showed a statistically significant increase in the older groups (p = 0,043). While VST, relative wall thickness, LVM, and LVMi showed no significant differences between the age categories. In turn, the shortening fraction and the ejection fraction increase with age. 

Conclusion For a more sensitive morphological and functional assessment of the left ventricle, it is necessary to take into account the gender and age of the individual.

Keywords: Two-dimensional Echocardiography; Global Longitudinal Strain; Speckle tracking; Systolic Function


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Citation: Humberto Morais., et al. "Global Longitudinal Strain and Echocardiographic Parameters of Left Ventricular Geometry and Systolic Function in Healthy Adult Angolans: Effect of Age and Gender. A Pilot Study”. EC Cardiology 8.9 (2021): 14-22.

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