Research Article
Volume 8 Issue 4 - 2021
Device Therapy in Ischemic Heart Disease: Are we there yet?
Hilaryano Ferreira*, Inês Fialho, Maura Nédio, Elsa Lourenço, Ana Rita Ferreira, Mariana Faustino, Marco Beringuilho, Nuno Cabanelas, Francisco Madeira and Carlos Morais
Department of Cardiology, Hospital Professor Doutor Fernando Fonseca, Lisbon, Portugal
*Corresponding Author: Hilaryano Ferreira, Department of Cardiology, Hospital Professor Doutor Fernando Fonseca, Lisbon, Portugal.
Received: January 07, 2021; Published: March 18, 2021


Background: More than a decade has passed since the publication of landmark randomized controlled trials on primary prevention of sudden cardiac death, which have served until the present as the basis for implantable cardiac defibrillator use in patients with left ventricle systolic dysfunction and heart failure. Recent studies have shown that patients with reduced ejection fraction may improve over time and some of these patients will receive a defibrillator without a clear need. We hypothesized that patients with ischemic heart disease are being better managed, faster and with newer medical therapies and thus, resulting in a reduction of mortality and need for implantable cardiac device therapy.

Methods: Retrospective cohort study of 655 patients with acute coronary syndrome. Primary outcome: 1-year mortality rate and unplanned revascularization. Secondary outcome: incidence of cardiac device implantation for primary prevention of sudden cardiac death. Follow-up period of 633 days.

Results: Median age 65 years, male 68,7%. 403 (61.3%) with non-ST elevation myocardial infarction and 252 (38.5%) with ST elevation myocardial infarction, underwent invasive coronary angiography. One-year mortality occurred in 3.8%, and unplanned revascularization in 8,2%. 98 patients received device therapy for primary prevention of sudden cardiac death.

Conclusion: There is trend towards reduction in mortality and cardiac device therapy implantation in patients with ischemic cardiomyopathy.


Keywords: ST Elevation; Myocardial Infarction; Cardiac Device Therapy Implantation


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Citation: Hilaryano Ferreira., et al. “Device Therapy in Ischemic Heart Disease: Are we there yet?”. EC Gynaecology 8.4 (2021): 05-12.

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