Case Report
Volume 7 Issue 10 - 2020
Vitamin D Deficiency in the Setting of Multiple Sclerosis - A Case Report and Literature Review
Ramy Ibrahim1*, Jose Ruben Hermann2, Irina Dashkova3 and Anna Dashkova4
1Medical Director, Premier Medical Associates, The Villages, Florida, USA
2Clinical Care Coordinator/Foreign MD, Premier Medical Associates, The Villages, Florida, USA
3Assistant Professor, Hofstra Northwell School of Medicine, USA
4Department of Biology, Hofstra University, USA
*Corresponding Author: Ramy Ibrahim, Medical Director, Premier Medical Associates, The Villages, Florida, USA.
Received: September 16, 2020; Published: September 30, 2020


Introduction: Multiple sclerosis (MS) is a chronic idiopathic inflammatory disorder of the central nervous system, characterized pathologically by demyelination and subsequent axonal degeneration. The disease commonly presents in young adults and affects twice as many women as men. Clinical presentation include numbness, weakness, visual impairment, loss of balance, dizziness, urinary bladder urgency, fatigue, and depression among many other unspecific symptoms. A higher MS risk in individuals with low vitamin D intake or low circulating 25-dihydroxyvitamin D as well as a reverse correlation between vitamin D levels and MS activity have been reported and suggest that vitamin D is related to the disease process that leads to and perpetuates MS. In this case report, we present a patient with MS and low levels of Vitamin D.

Case Presentation: A 35-year-old female was seen in the Emergency room complaining of 3 days of acute polymyalgia and worsening chronic right-sided hemiparesis. Her past neurological history is significant for acute right-sided hemiplegia during the 2nd trimester of her third pregnancy in 12-24-2013 when she was admitted to the hospital and -according to the patient- diagnosed with possible Multiple sclerosis according to a Cerebral spinal fluid (CSF), Neurology evaluation and ophthalmologic evaluation confirming Optic Neuritis. On her day of admission, her labs were unremarkable except for a Vitamin D level of 10 ng/mL. Her work-up at that time was limited due to her pregnancy.

Conclusion: MS patients who present with Vitamin D deficiency should be closely monitored to prevent the aforementioned deficiency. Additionally, the risk of developing MS could be reduced by upholding optimal vitamin D levels in the healthy population. Further randomized interventional trials are definitely required to elucidate the therapeutic effect of vitamin D in MS.

Keywords: Multiple sclerosis (MS); Central Nervous System (CNS); Vitamin D


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Citation: Ramy Ibrahim., et al. “Vitamin D Deficiency in the Setting of Multiple Sclerosis - A Case Report and Literature Review”. EC Cardiology 7.10 (2020): 54-59.

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