Review Article
Volume 7 Issue 7 - 2020
Cardiovascular Benefits of Turmeric (Curcumin) in Humans: Evidence from Clinical Trials
Sunil Reddy D
Head, Department of Cardiology, Russh Superspeciality Hospital, Hyderabad, Telangana, India
*Corresponding Author: Sunil Reddy D, Head, Department of Cardiology, Russh Superspeciality Hospital, Hyderabad, Telangana, India.
Received: June 06, 2020; Published: June 26, 2020




Abstract

Turmeric has been used for centuries in alternative system of medicine (ASM) for treating multiple ailments owing to its organoleptic, protective and therapeutic effects. Curcumin is a major active component of turmeric which is extracted from the dry rhizome of Curcuma longa. A major limitation to using curcumin as a therapeutic agent is its poor bioavailability.

Although numerous animal studies have shown promising cardiovascular benefits of curcumin, very few human studies have been conducted till date addressing the cardiovascular benefits of curcumin in humans. There is variability in curcumin metabolism between humans and animals limiting the validity and extrapolation of the results of animal studies to humans. This review consolidates the available evidence from human studies which have reported the effects of curcumin on various causative factors implicated in pathophysiology of cardiovascular disease. Positive results with curcumin were seen in studies reporting anti-inflammatory activity, antioxidant activity, effect on endothelial function, metabolic syndrome and in post cardiac surgery settings, with insignificant or mixed results in other factors studied. Larger and well randomized studies need to be conducted to establish the possible therapeutic role of curcumin, if any, in primary and secondary prevention of various cardiovascular diseases.

Keywords: Cardiovascular; Turmeric (Curcumin); Human trials

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Citation: Sunil Reddy D. “Cardiovascular Benefits of Turmeric (Curcumin) in Humans: Evidence from Clinical Trials”. EC Cardiology 7.7 (2020): 24-31.

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