Guest Editorial
Volume 7 Issue 4 - 2020
Diseases of Lifestyle and Unhealthy Diet: Editorial
Gundu HR Rao*
Emeritus Professor, Laboratory Medicine and Pathology Director, Thrombosis Research, Lillehei Heart Institute, University of Minnesota, USA
*Corresponding Author: Gundu HR Rao, Emeritus Professor, Laboratory Medicine and Pathology Director, Thrombosis Research, Lillehei Heart Institute, University of Minnesota, USA.
Received: February 27, 2020; Published: March 01, 2020

Twin epidemics of obesity and diabetes have reached epidemic proportions worldwide, and there seems to be no signs whatsoever, that this trend will reverse in the near future. Malnutrition in all its forms, including obesity, undernutrition, and other dietary risks, is the leading cause of poor health globally [1]. Results of a recent study, by the Lancet Public Health Investigators, shows an alarming extent of obesity’s impact on health [2]. The authors conclude, that the effect of obesity through NCDs, is likely to be more alarming than reported by the Global Public Health Groups [2]. Systematic reviews of a large data-base suggests, that determining obesity based on Body Mass Index (BMI), has low to moderate sensitivity, and is quite conservative for all ages and sexes. The prevalence of adult overweight and obesity, as defined using BMI has increased worldwide since the 1980s, with no country demonstrating any successful decline in the last four decades. Recently, the International Atherosclerosis Society (IAS) and International Chair on Cardiometabolic Risk (ICCR) Working Groups, issued a Consensus Statement, “Waist circumference as a vital sign in clinical practice”. A bilateral study between the University of Minnesota researchers, and the staff of Madras Diabetes Research Foundation (MDRF), Chennai, India, reported their findings on the importance of waist circumference on determining obesity [3].


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  3. Bajaj HS., et al. “Comparison of relative waist circumference between Asian and US adults”. Journal of Obesity (2014): 461956.
  4. Ng M. “Global regional, and national prevalence of overweight and obesity in children and adults during 1980-2013: a systematic analysis for the Global Burden of Diseases Study 2013”. Lancet 384 (2013): 766-781.
  5. Ross R., et al. “Waist circumference as a vital sign in clinical practice: A Consensus Statement from the IAS and ICCR Working Group on Visceral Obesity”. Nature Reviews Endocrinology 16.3 (2020): 177-189.
  6. Reilly JJ., et al. “Determining the worldwide prevalence of obesity”. Lancet Public Health 391.101320 (2018): 1773-1774.
  7. Harding JL., et al. “Global trends in diabetes complications: a review of current evidence”. Diabetologia 62.1 (2019): 3-16.
  8. Global Burden of Diseases 2016 Diseases and Injury Incidence and Prevalence Collaborators: Global Regional, and National Incidence. “Prevalence and years lived with disability for 328 days and injuries in 195 countries, 1990-2016: A systematic analysis for the global disease burden of disease study 2016”. Lancet 390.10100 (2017): 1211-1259.
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  11. Rao GHR. “Fetal Origin of adult cardiometabolic diseases: Micronutrient and microRNA Interventions”. EC Endocrinology and Metabolic Research 4.1 (2019): 7-16.
  12. Rao GHR and Bharathi M. “Mother and child nutrition: First major step for the prevention of Cardio-Metabolic Diseases”. The Journal for Cardiology - Photon Journal 109 (2016): 179-186.
  13. Yusuf S., et al. “Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case control study”. Lancet 364.9438 (2004): 937-952.
  14. Khera AV., et al. “Genetic risk, adherence to healthy lifestyle, and coronary artery disease”. New England Journal of Medicine 375 (2016): 2349-2358.
  15. Di Cesare M., et al. “The contributions of risk factor trends to cardiometabolic mortality decline in 26 industrialized countries”. International Journal of Epidemiology 42.3 (2013): 838-848.
  16. Rajati F., et al. “Prevalence, awareness, treatment and control of hypertension and their determinants: Results from the first cohort of non-communicable diseases in Kurdish settlement”. Scientific Reports 9.1 (2019): 12409.
  17. Kumanyika SK., et al. “Population-based Prevention of Obesity: The need for comprehensive promotion of human healthful eating, physical activity, and energy balance: A scientific statement from American Heart Association Council on Epidemiology and Prevention, Interdisciplinary Committee for Prevention (Formerly the expert panel on population and prevention sciences”. Circulation 118.4 (2008): 428-464.
  18. Hallberg SJ., et al. “Reversing Type-2 diabetes: A narrative review of the evidence”. Nutrients 11.4 (2019): 766. 
Citation: Gundu HR Rao. “Diseases of Lifestyle and Unhealthy Diet: Editorial”. EC Cardiology 7.4 (2020): 01-04.

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