Short Communication
Volume 7 Issue 3 - 2020
Tako-Tsubo Syndrome: A Latent Disease
Claribel Plain Pazos1*, Carmen Rosa Carmona Pentón1, Elsa Núñez Escobar2, Anisbel Pérez de Alejo Plain3, René Vázquez Estévez4, Roberto N Aguiar Delgado5, Yilian Burgos Santos6 and Bárbara Marrero Diaz7
1Specialist of II Degree in Comprehensive General Medicine, Assistant Professor, Faculty of Medical Sciences of Sagua la Grande, Villa Clara, Cuba
2Specialist of I Degree in Comprehensive General Medicine, Assistant Professor, Faculty of Medical Sciences of Sagua la Grande, Villa Clara, Cuba
3rd Year Student of Medicine, Medical Faculty of Medical Sciences of Sagua la Grande, Villa Clara, Cuba
4Specialist of I Degree in Surgery, Assistant Professor, Teaching General Teaching Hospital “Mártires del 9 de Abril”, Sagua la Grande, Villa Clara, Cuba
5Specialist of I Degree in Gynecology, Assistant Professor, Teaching General Teaching Hospital “Mártires del 9 de Abril”, Sagua la Grande, Villa Clara, Cuba
6Specialist of I Degree in Internal Medicine, Assistant Professor, Teaching General Teaching Hospital “Mártires del 9 de Abril”, Sagua la Grande, Villa Clara, Cuba
7Specialist of I Degree in Comprehensive General Medicine, Assistant Professor, “Idalberto Revuelta” Clínic of Sagua la Grande, Villa Clara, Cuba
*Corresponding Author: Claribel Plain Pazos, Specialist of II Degree in Comprehensive General Medicine, Assistant Professor, Faculty of Medical Sciences of Sagua la Grande, Villa Clara, Cuba.
Received: January 18, 2020; Published: February 26, 2020

The first description of Takotsubo syndrome (TTS), also known as broken heart syndrome, apical dyskinesia syndrome, stress-induced cardiomyopathy, apical bulge syndrome or ampullary cardiomyopathy was made in 1990 [1-4] by Dr. Hikaru Sato, who reported a left ventricular dysfunction, which acquired a silhouette similar to an old Japanese vessel used to fish octopus (tako = octopus, tsubo = vessel) [5], although it is in 2001 when it was consolidated as an independent entity, described by Tsuchihashi et al again in Japan the first series of 88 patients [1,6]. The first case reported in Latin America was in 2004 in Mexico and in 2017 the first record of a series of patients in Latin America was published in Chile [7].


  1. Tsuchihashi K., et al. "Transient left ventricular apical ballooning without coronary artery stenosis: a novel heart syndrome mimicking acute myocardial infarction". Journal of the American College of Cardiology 38 (2001): 11-18. 
  2. Ghadri JR., et al. "International expert consensus document on Takotsubosyndrome (part I): clinical characteristics, diagnostic criteria, and pathophysiology". European Heart Journal 39.22 (2018): 2032-2046.
  3. Morales Hernández AE., et al. "Síndrome de Takotsubo". Medicina Interna de México 32.4 (2016).
  4. Aguirre E M., et al. "Cardiomiopatía de tako-tsubo en un paciente con estenosis aórtica moderada. Caso clínico y revisión bibliográfica". Revista Metro Ciencia 26.1 (2018): 16-20. 
  5. Espinoza Alva D., et al. "Características clínicas y complicaciones del síndrome de Takotsubo en un centro de referencia de la seguridad social peruana" . Revista Peruana de Medicina Exp Salud Publica 36.2 (2019): 255-259.
  6. Sénior JM., et al. "Cardiomiopatía de Takotsubo". Iatreia 28.2 (2015): 202-206. 
  7. Arandia Guzmán J., et al. "Miocardiopatía inducida por estrés o síndrome de Takotsubo: a propósito de un caso". Gaceta Medica Boliviana 41.1 (2018): 71-74.  
  8. Obón Azuara B., et al. "Cardiomiopatía de takotsubo: disfunción transitoria apical de ventrículo izquierdo". Medicina intensiva 31.3 (2007): 146-152.
  9. Pelliccia F., et al. "Pathophysiology of Takotsubo syndrome". Circulation 135.24 (2017): 2426-2441.
  10. Bermúdez Yera GT., et al. "Takotsubo en el postoperatorio de reemplazo valvular mitral". CorSalud 11.3 (2019): 263-267.
  11. Gaspar J., et al. "Síndrome Tako-Tsubo (Discinesia antero-apical transitoria): Primer caso descrito en América Latina y revisión de la literatura". Archivo Cardiología México 74.3 (2004): 205-214. 
  12. Gumucio Charro R., et al. "Síndrome del corazon roto, El gran imitador de infarto agudo de miocardio: relato de un caso". Revista Médico Científica "Luz Vida" 9.1 (2017): 43-47.
  13. Ghadri JR., et al. "International expert consensus document on Takotsubo syndrome (part II): diagnostic workup, outcome, and management". European Heart Journal 39.22 (2018): 2047-2062.
  14. Ortiz Lasa M., et al. "Síndrome de takotsubo secundario a traumatismo raquimedular". Revista Colombiana de Cardiología 25.3 (2018): 237-237.
Citation: Claribel Plain Pazos., et al. “Tako-Tsubo Syndrome: A Latent Disease”. EC Cardiology 7.3 (2020): 01-04.

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