Review Article
Volume 5 Issue 8 - 2022
Stress: Its Mechanism, Experimental Assessment and Diagnostic Markers

Mohd Rafi Reshi1*, Nusrat Nabi1, Afshana Bashir Reshi2, Aabida Majid3, Saman Anees4, Nafaa Hasan1, Maaz Naqvi1 and Jamal Akhtar5

1Department of Pharmacology Hamdard Institute of Medical Sciences and Research, Jamia Hamdard University, New Delhi India

2DRDO Associated Hospital, Government Medical College, Srinagar, Jammu and Kashmir, India

3Government Amt School Shireenbagh, Govt. Medical College, Srinagar, Jammu and Kashmir, India

4Department of Amraze Niswan Wa Atfal, SUMER, Jamia Hamdard University New Delhi, India

5Cetral Council for Research in Unani Medicine, Janikpuri, New Delhi, India

*Corresponding Author: Mohd Rafi Reshi, Department of Pharmacology Hamdard Institute of Medical Sciences and Research, Jamia Hamdard University, New Delhi India.
Received: July 28, 2022; Published: August 18, 2022




Abstract

Stress is linked to the central nervous system. In addition to its primary function in the body, it also assists in body upkeep. As a result, its proper operation is critical for both health and sickness. When the central nervous system is out of equilibrium, the CNS system's mechanism changes. Understanding the mechanism of stress is crucial for developing pharmaceutical methods for its prevention. Among the common molecular pathways contributing to impaired brain function are inflammation, immunomodulation and oxidative stress. A variety of drugs and chemicals are used to experimentally induce stress of CNS, which are assessed in the laboratory by physiological, physically, emotionally and pathological biomarkers. The present review outlines some of the fundamental ideas in stress, as well as several preclinical screening methodologies and diagnostic markers.

 

Keywords: Stress; Brain; Markers; Diseases

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Citation: Mohd Rafi Reshi., et al. “Stress: Its Mechanism, Experimental Assessment and Diagnostic Markers”. EC Clinical and Medical Case Reports 5.8 (2022): 75-88.

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