Case Report
Volume 5 Issue 6 - 2022
Allergic Bronchopulmonary Aspergillosis (ABPA) in a Middle Aged Man camouflaged by Atopic Chronic Persistent Bronchial Asthma
Richmond Ronald Gomes*

Medicine, Ad-din Women’s Medical College Hospital, Bangladesh

*Corresponding Author: Richmond Ronald Gomes, Medicine, Ad-din Women’s Medical College Hospital, Bangladesh.
Received: April 20, 2022; Published: May 27, 2022




Abstract

Allergic bronchopulmonary aspergillosis (ABPA) is an allergic pulmonary disease characterized by an exaggerated immune response (a hypersensitivity response) to the fungus Aspergillus (most commonly Aspergillus fumigatus) with a variable radiographic appearance. ABPA most commonly affects patients with steroid-dependent asthma (1 - 2%) and patients with cystic fibrosis (5 - 15%). ABPA is very rarely diagnosed in non-asthmatics. Clinical features of ABPA are wheezing, mucoid impaction, and pulmonary infiltrates. Oral corticosteroids and anti-fungal agents are standard therapy for ABPA. ABPA causes airway inflammation that if left untreated can lead to bronchiectasis (an abnormal dilation of the airways) due to the immune system and fungal spores damaging sensitive lung tissues and ultimately leading to scarring. We report a case of ABPA in a 40-year-old male initially evaluated for poorly controlled chronic persistent bronchial asthma. After the diagnostic investigation was complete, the diagnosis of ABPA was established and appropriate treatment was instituted leading to clinical, radiological, and serological improvement.

Keywords: Aspergillus Fumigates; Hypersensitivity; Steroid-Dependent Asthma; Wheezing; Bronchiectasis

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Citation: Richmond Ronald Gomes. “Allergic Bronchopulmonary Aspergillosis (ABPA) in a Middle Aged Man camouflaged by Atopic Chronic Persistent Bronchial Asthma”. EC Clinical and Medical Case Reports 5.6 (2022): 32-39.

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