Abstract
Granulomatous mastitis is a rare inflammatory breast disease. It usually occurs in premenopausal patients and its ethology is unknown.
The appearance of a unilateral inflammatory breast tumor is usually the most frequent clinical finding.
Clinically and radiologically it is very similar to breast carcinoma or tuberculosis. We must take into account this pathology especially in case of negative persistent cultures and inconclusive biopsies.
The diagnosis is obtained by biopsy. Histologically we will find a chronic granulomatous necrotizing lobulitis with microabscesses.
The treatment of this disease consists of antibiotic therapy prior to corticosteroids, in cases of poor evolution methotrexate can be added.
Keywords: Breast Inflammation; Granulomatous Mastitis
References
- M Jimenez González and A Melero López. “Mastitis granulomatosa”. Elsevier Volume 42. Number 3 (2015): 141-144.
- Tuli R., et al. “Idiopathic granulomatous mastitis masquerading as carcinoma of the breast: A case report and review of the literature”. International Seminars in Surgical Oncology 4 (2007): 21.
- Akbulut S., et al. “Methotrexate in the management of idiopathic granulomatous mastitis: Review of 108 published cases and report of four cases”. Breast Journal 6 (2011): 661-668.
- Hugon-Rodin J., et al. “Management of granulomatous mastitis: A series of 14 patients”. Gynecological Endocrinology 11 (2012): 921-924.
- Gurleyik G., et al. “Medical surgical treatment of idiopathic granulomatous lobular mastitis: A benign inflammatory disease mimicking invasive carcinoma”. Journal of Breast Cancer 1 (2012): 119-123.
- Peña Santos G and Ruíz Moreno JL. “Granulomatous mastitis treated with steroids and methotrexate”. Ginecologia y Obstetricia de Mexico 6 (2011): 373-376.
- Alonso Amigo MA., et al. “Mastitis granulomatosa”. Progresos de Obstetricia y Ginecología 54 (2011): 144-147.
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