Review Article
Volume 5 Issue 1 - 2022
Adjuvanticity of Aloe Vera Gel and the Role of Butyrate Fermented as an Adjuvant for COVID-19 Vaccination
Akira Yagi1* and Byun P Yu2
1Special Advisor of Japan Aloe Science Association, Professor, Emeritus of Fukuyama University, Hiroshima, Japan
2Professor Emeritus of University of Texas, Heath Science Center, Department of Physiology, San Antonio, Texas, USA
*Corresponding Author: Akira Yagi, Special Advisor of Japan Aloe Science Association; Professor Emeritus of Fukuyama University, Hiroshima, Japan.
Received: December 08, 2021; Published: December 30, 2021


Adjuvants are added to vaccinations to boost their immunogenicity. We reviewed what we know about how butyrate affects immunity and adjuvant action. The usefulness of Aloe vera, aloe vera gel polysaccharide (acemannan), and butyrate fermented adjuvants in increasing Covid-19 immunization efficacy was thoroughly investigated. Butyrate, a known histone deacetylase inhibitor that stimulates expression of numerous genes involved in immune system pathways, was studied extensively for its adjuvanticity and effects on virus infection.

Keywords: Adjuvanticity; Aloe Vera Gel; Butyrate Fermented; Covid-19 Va


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Citation: Akira Yagi and Byun P Yu. “Adjuvanticity of Aloe Vera Gel and the Role of Butyrate Fermented as an Adjuvant for COVID-19 Vaccination”. EC Clinical and Medical Case Reports 5.1 (2022): 21-26.

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