Case Report
Volume 4 Issue 12 - 2021
Effect of Omega 3 Fatty Acids Supplementation on Patency of Arteriovenous Access in Hemodialysis Patients

Walid Ahmed Bichari and Ahmed Mohamed Alsawy*

Department of Internal Medicine and Nephrology, Faculty of Medicine, Ain Shams University, Egypt
*Corresponding Author: Ahmed Mohamed Alsawy, Department of Internal Medicine and Nephrology, Faculty of Medicine, Ain Shams University, Egypt.
Received: November 01, 2021; Published: November 29, 2021


Background: Maintaining vascular access in hemodialysis patient is considered a challenge since the portal is vulnerable to infection, stenosis, and thrombosis.

Aim of the Work: Evaluate the role of ω-3 fatty acids in preserving the patency of arteriovascular fistulas and grafts in hemodialysis patients.

Patients and Methods: A prospective randomized case control study conducted on 80 chronic hemodialysis patients who are currently undergoing hemodialysis three sessions per week for more than 3 months in our hospital (El-Maadi Liver and kidney transplantation hospital). The study was conducted through a period of time spanning 6 months.They were divided into two groups;

Group 1: (40 hemodialysis patients receiving ω-3 fatty acids for 6 months)

Group 2: (40 hemodialysis patients not receiving ω-3 fatty acids). Patients were assigned to receive fish oil capsules (four 1-g capsules/d) for the 6-month duration of the study. The fish oil was omega 3, which contains 18% eicosapentaenoic acid (EPA) and 12% docosahexaenoic acid (DHA).

Results: In our study there was increase in blood flow in group 1 more than in group 2 but not reaching a statistically significant difference. In our study there was highly significant statistical decrease in blood flow in 1st, 2nd, 3rd, 4th, 5th and 6th month in comparison to Basal in both two groups (p < 0.001). In our study there was highly significant statistical increase in URR in group 1 compared to group 2 over the six months period (p < 0.001). Conclusion: Among patients with arteriovenous hemodialysis grafts and fistulas, daily ingestion of fish oil leads to highly significant statistical decrease in triglyceride level, total cholesterol level and LDL cholesterol level and increase in HDL cholesterol level. Blood flow also increased but not reaching a statistically significant difference.

Keywords: omega 3; Arteriovenous Access; Hemodialysis


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Citation: Walid Ahmed Bichari and Ahmed Mohamed Alsawy. “Effect of Omega 3 Fatty Acids Supplementation on Patency of Arteriovenous Access in Hemodialysis Patients". EC Clinical and Medical Case Reports 4.12 (2021): 14-22.

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