Case Report
Volume 4 Issue 4 - 2020
Adrenal Insufficiency in a Mosaic Klinefelter Syndrome
Ramy Ibrahim1*, Mazen M Salama2, Ereny Demian3 and Herman Lebovtch4
1Medical Director, Head of Research, Premier Medical Associates, The Villages, Florida, USA
2Healthcare Data Scientist MD MSc CPDS, Utah, USA
3Research Volunteer, Premier Medical Associates, The Villages, Florida, USA
4MD Vice Chairman , Department Of Medicine , Brookdale University Hospitals, New York, USA
*Corresponding Author: Ramy Ibrahim, Medical Director, Head of Research, Premier Medical Associates, The Villages, Florida, USA.
Received: March 02, 2021; Published: March 19, 2021


We report a rare presentation of Klinefelter with an adrenal insufficiency diagnosed in a late stage of life. A 52 years old white male was admitted to MICU after a suicidal attempt by drinking three bottles of isopropyl alcohol. The patient presented with lethargy and altered mental status, and severe hypothermia of 34.5°C as he was found exposed during a snowstorm. Later, he was admitted to MICU with severe hypotension that was treated with fluid challenge and pressors. Cosyntropin test revealed hypoadrenalism. The patient disclosed a condition of Mosaic karyotype of Klinefelter syndrome, which was attributed as a cause of his hypoadrenalism.

Keywords: Klinefelter Syndrome; Mosaic Karyotype; Adrenal Insufficiency


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Citation: Ramy Ibrahim., et al. “Adrenal Insufficiency in a Mosaic Klinefelter Syndrome”. EC Clinical and Medical Case Reports 4.4 (2021): 39-43.

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