Case Report
Volume 4 Issue 2 - 2021
Exploratory Approaches for the Use of Coenzyme Q10 with Aloe Vera Gel for Leber’s Hereditary Optic Neuropathy: Case Report
Megumi Hasegawa1, Akira Yagi2* and Suzuka Ataka3
1Pharmacist, Kampo Pharmacy Grace-Meg-Salon, Toshima-ku, Tokyo, Japan
2Special Adviser of Japan Aloe Science Association and Emeritus Professor, Fukuyama University, Hiroshima, Japan
3The Director of Med Cell Clinic, Osaka, Kita-ku, Umeda, Osaka, Japan
*Corresponding Author: Akira Yagi, Special Adviser of Japan Aloe Science Association and Emeritus Professor, Fukuyama University, Hiroshima, Japan.
Received: January 21, 2021; Published: January 30, 2021


There are currently no proven treatments for Leber’s hereditary optic neuropathy (LHON; Designation criteria for LHON: Intractable disease 302). Symptomatic treatment and genetic counselling are important in the management of patients with LHON. Idebenone and CoQ10 may prove useful in the treatment of patients with LHON as free radical scavengers. CoQ10 deficiency leads to mitochondrial encephalomyopathy due to interruption of oxidative phosphorylation. Bioavailability treatment of CoQ10 by oral CoQ10/γ cyclodextrin is beneficial in LHON patients. Here we discuss the role of fat-soluble CoQ10 with aloe vera supplementation for LHON patient on the standard point of bioavailability and butyrate-induced modulation of gene expression and cellular function. Lastly, we exhibited a case report of LHON patient by using a lot of CoQ10 with aloe vera supplementation.

Keywords: Coenzyme Q10; Aloe Vera Gel; Leber’s Hereditary Optic Neuropathy


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