Case Report
Volume 3 Issue 11 - 2020
Fullerene - Photodynamic Therapy Effect on Oral Squamous Cell Carcinoma of the Tongue: A Case Study
Deborah D Viglione1and Daniel J Bourassa2,3*
11Director, Living Waters Regenerative Medicine Center, Gulf Breeze, FL, USA
2Einstein Medical Institute, North Palm Beach, FL, USA
3University of Health and Humanities, Tortola, British Virgin Islands
*Corresponding Author: Daniel J Bourassa, Einstein Medical Institute, North Palm Beach, FL, USA.
Received: September 05, 2020; Published: October 19, 2020




Abstract

Photodynamic therapy produces localized Type 1 and Type 2 photochemical damage in targeted cancer cells. It has been established as a safe and non-invasive modality in the treatment of squamous cell carcinoma, as well as other tumors. Fullerenes have demonstrated tremendous potential as photosensitizers due to their excellent biocompatibility and unique characteristics. Here we present the case of an oral squamous cell carcinoma (OSCC) on the tongue of a 50-year-old female who underwent a limited course of photodynamic therapy (PDT) using a pristine nanocarbon onion-like fullerene (NOLF) before undergoing surgical excision. The fullerene- PDT treatment using violet and blue light resulted in a significant reduction in the size and appearance of the lesion. Additionally, the use of pristine (NOLF) as a photosensitizer has never been reported in the literature to our knowledge.

Keywords: Fullerenes; Nanocarbon Onion-Like Fullerenes; Oral Squamous Cell Carcinoma; Photodynamic Therapy; Type 1 Photochemistry; Type 2 Photochemistry

References

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Citation: Deborah D Viglione and Daniel J Bourassa. “Fullerene - Photodynamic Therapy Effect on Oral Squamous Cell Carcinoma of the Tongue: A Case Study”. EC Clinical and Medical Case Reports 3.11 (2020): 25-29.

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