Literature Review
Volume 3 Issue 8 - 2020
Rare Clinical Manifestations; Priapism in Chronic Myeloid Leukemia-A Review
Anmol Sultan1, Muhammad Inam Ul Haq2, Ahsan Ali Khan Salik2, Syed Zeeshan Tirmizi2, Wareesha Afaq Zaidi2, Syed Wasi Ahsan Ahmad2, Nadeem Iqbal3* and Kamran Majeed3
1Lahore Medical and Dental College, Lahore, Pakistan
2Shifa College of Medicine, Islamabad, Pakistan
3Department of Urology, Shifa International Hospital, Islamabad, Pakistan
*Corresponding Author: Nadeem Iqbal, Department of Urology and Kidney Transplant, Pakistan Kidney Institute, Shifa International Hospital, Islamabad, Pakistan.
Received: June 21, 2020; Published: July 31, 2020




Abstract

Chronic myeloid leukemia (CML) is a characterized by a chronic myeloproliferative disorder manifesting routinely with increased number of white blood cells and huge splenomegaly. Mostly it has an insidious nature with nonspecific set of symptoms such as tiredness, fever, or associated weight loss. At rare occasions priapism can also happen in course of CML. Its pathogenesis is ascribed to hyper leukocytosis and resultant increased viscosity. The treatment for such crises often involves oncologic and urology intervention. Due to the rarity of the manifestation of priapism in CML patients, the management remains controversial. Majority of the authors advocate CML-specific therapy (chemotherapy) alone, whereas some advocate additional urological intervention. It is not only a medical emergency but also a urological one, needing prompt therapy. In this review we tried to explain the importance of diagnosing this rare clinical challenge in time and taking the possible available measures to deal with it in terms of necessary work-up and management of such patients.

Keywords: Chronic Myeloid Leukemia (CML); Priapism; Chronic Myeloproliferative Disorder

References

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Citation: Nadeem Iqbal., et al. “Rare Clinical Manifestations; Priapism in Chronic Myeloid Leukemia-A Review”. EC Clinical and Medical Case Reports 3.8 (2020): 96-101.

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