Review Article
Volume 3 Issue 7 - 2020
Review of 8 Hydroxy 2 Deoxyguanosine and 8-Isoprostane as Biomarkers of Oxidative Stress in Respiratory Diseases
Aneza Jalil1* and Shoeb Ahmed Ilyas2
1Pakistan Institute of Medical Science, Islamabad, Pakistan
2Ruby Med Plus, Hyderabad, Telangana, India
*Corresponding Author: Aneeza Jalil, Pakistan Institute of Medical Science, Islamabad, Pakistan.
Received: April 25, 2020; Published: June 29, 2020




Abstract

Lately, the emphasis has been given to the importance of oxidative stress as the determinants of respiratory diseases like Asthma, Chronic Obstructive Pulmonary Disease (COPD) and allergic rhinitis. Oxidative stress is a very important caution signal, fundamental for early diagnosis and treatment of respiratory illness. The significance of oxidative stress on the pathogenesis and development of respiratory diseases is partly recognized, as the mechanisms and importance of the process are still unknown. The increasing oxidant pollutant exposures have detrimental effects on public health as inhaled oxidants stimulate pathologic processes like airways inflammation and aggravation of airways disease. Hence it is critical to understand the mechanisms of oxidants and their impact on respiratory illness. This study aims to review 8 hydroxy 2 deoxyguanosine and Isoprostane biomarkers of oxidative stress in respiratory diseases. Measurement of these biomarkers of oxidative stress explores the role of free radicals in the pathogenesis, risk stratification and prognosis of conditions associated with oxidative stress in respiratory diseases. Thus, the incidence of oxidative stress has vital consequences in the pathogens of asthma, allergic rhinitis, and COPD..

Keywords: Oxidative Stress; Biomarkers; 8 Hydroxy 2 Deoxyguanosine; 8-Isoprostane; Chronic Obstructive Pulmonary Disease; Asthma; Rhinitis

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Citation: Aneza Jalil and Shoeb Ahmed Ilyas. “Review of 8 Hydroxy 2 Deoxyguanosine and 8-Isoprostane as Biomarkers of Oxidative Stress in Respiratory Diseases”. EC Clinical and Medical Case Reports 3.7 (2020): 106-110.

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