Case Report
Volume 3 Issue 6 - 2020
A Huge Gastric Gastrointestinal Stromal Tumor in 45 Year Old Ethiopian Patient
Berhenu Kotiso1, Hailu Wondimu Gebresellassie2* and Zelalem Assefa2
1Professor of Surgery, Department of Surgery, AAU, CHS, SOM, Addis Ababa, Ethiopia
2Consultant Surgeon and Assistant Professor of Surgery, Department of Surgery, AAU, CHS, SOM, Addis Ababa, Ethiopia
*Corresponding Author: Hailu Wondimu Gebresellassie, Consultant Surgeon and Assistant Professor of Surgery, Department of Surgery, AAU, CHS, SOM, Addis Ababa, Ethiopia.
Received: February 29, 2020; Published: May 04, 2020




Abstract

Background: Gastrointestinal stromal tumors (GISTs) are soft tissue sarcomas that arise from specialized interstitial cells of cajal (ICCs) in the walls of GI tract. Although stomach is the commonest site of origin the size of commonly encountered GISTs are small. Here we report a case of biggest gastric GIST weighing 20 kilograms ever reported in 45 years old Ethiopian patient.

Case Presentation: A 45 years old Ethiopian patient presented with an abdominal pain and a progressive abdominal distension of one year duration. Physical examination revealed a chronically sick looking patient with a pale conjunctiva and distended abdomen. There was a huge mass filling the whole abdomen. Abdominal U/S revealed a huge heterogeneous mass filling whole abdomen with some free fluid collection in the peritoneal cavity. CT scan showed a complex mass filling the whole abdomen arising from the greater curvature of stomach posteriorly with calcifications and minimal ascites.

Surgery revealed a mass arising in the stomach attached to transverse colon and spleen with minimal ascites. The mass was excised with sleeve of stomach, part of transverse colon and spleen. The patient had smooth postoperative course and was discharged on the 7th postoperative day and followed for 3 months. Biopsy revealed the mass to be a gastrointestinal stromal tumor.

Conclusion: GISTs though rarely can present as a huge intra-abdominal mass.

Keywords: Gastric; GISTs; Intra-Abdominal Mass; Huge

References

  1. Raut JMP. “Epidemiology, classification, clinical presentation, prognostic features, and diagnostic work-up of gastrointestinal stromal tumors (GIST)”. UpToDate (2018).
  2. Carrillo Colmenero AM., et al. “Giant Primary Extra Gastrointestinal Stromal Tumor of the Liver”. Cirugía Española (English Edition)9 (2017): 547-550.
  3. Raut JMP. “Local treatment for gastrointestinal stromal tumors, leiomyomas, and leiomyosarcomas of the gastrointestinal tract”. UpToDate (2018): 1689-1699.
  4. Miyazaki R., et al. “A Giant Gastrointestinal Stromal Tumor of the Stomach with Extramural Growth”. Case Reports in Gastroenterology 2 (2016): 344-351.
  5. Mohamed A., et al. “Gigantic GIST: A Case of the Largest Gastrointestinal Stromal Tumor Found to Date”. Case Reports in Surgery (2018): 1-5.
  6. Koyuncuer A., et al. “A rare case of giant gastrointestinal stromal tumor of the stomach involving the serosal surface”. International Journal of Surgery Case Reports 12 (2015): 90-94.
  7. Misawa S ichi., et al. “Spontaneous rupture of a giant gastrointestinal stromal tumor of the jejunum: A case report and literature review”. World Journal of Surgical Oncology 1 (2014): 153.
  8. Wang L., et al. “Giant gastrointestinal stromal tumor with predominantly cystic changes: A case report and literature review”. World Journal of Surgical Oncology 1 (2017): 220.
  9. Fukuda S., et al. “Giant gastric gastrointestinal stromal tumor with severe peritoneal dissemination controlled by imatinib therapy following debulking surgery: a case report”. Journal of Medical Case Reports 1 (2017): 33.
Citation: Hailu Wondimu Gebresellassie., et al. “A Huge Gastric Gastrointestinal Stromal Tumor in 45 Year Old Ethiopian Patient”. EC Clinical and Medical Case Reports 3.6 (2020): 05-09.

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