Research Article
Volume 3 Issue 11 - 2020
The Effect of Smoking, Hookah and Tobacco Consumption on Sperms Morphological Forms - Pilot Study
Ammar Mohammed Ali Mohammed1*, Gihad Eldeen Ibrahim Osman2, Nazik Ahmed Karar3 and Shimaa Osman Hassan2
1Assistant Professor, Faculty of Medicine, International University of Africa, Khartoum, Sudan
2Clinical Embryologist, Atrab and Enjab Fertility and IVF Center, Khartoum, Sudan
3IVF Lab Director, Atrab and Enjab Fertility and IVF Center, Khartoum, Sudan
*Corresponding Author: Ammar Mohammed Ali Mohammed, Assistant Professor, Faculty of Medicine, International University of Africa, Khartoum, Sudan.
Received: September 26, 2020; Published: October 30, 2020




Abstract

Background: Lifestyle factors like smoking or tobacco have negative impacts on male reproduction. Tobacco chewing and smoking habits in linked to significant decrease in semen quality, particularly sperm morphology. Semen morphology is an important parameter related to pregnancy. This study was designed to evaluate the effect of smoking, hookah and tobacco consumption on sperm quality and the related parameters such as sperm concentration and motility with focusing in detailed sperm morphology.

Patients and Methods: In this pilot study, we examined 20 male patients including control (patients with normal sperms' morphology and no history of nicotine consumption), smokers, Hookah and tobacco consumers. Semen analysis was done according to WHO 2010. For sperm morphology, smears made from semen samples and processed by using H&E technique. Normal and the abnormal sperms observed under 100× oil immersion microscope. Each of the spermatozoa was examined for head, mid piece and tail defects. A total of 200 spermatozoa were observed for defects and expressed in percentage for each sample.

Results: Patients' classified according to nicotine consumption into control 3, smokers 5, tobacco 5, hookah 2 and multiple 5. Nicotine consumption (smoking, Hookah and tobacco) strongly associated with semen analysis final report (P = 0.006). Sample volume mean 2.97 ± 1.11 ml. Sperm concentration 75 ± 51.5 Millions/ml. Sperm motility 47.05 ± 34.56 Millions/ml. Sperm morphology 2.85 ± 0.99%, Head malformation 72.2 ± 13.8%, Mid piece malformation 16.2 ± 9.5%, Tail malformation 7.4 ± 6.8% and Multiple defects 0.5 ± 1.1%. However, one case of triple tail sperm has been reported. Significant differences in means have been found regarding sperm concentration (P = 0.023), motility (P = 0.002), and morphology (P = 0.045).

Conclusion: Nicotine consumption significantly decrease semen quality by lowering concentration, motility and morphology. Different forms of sperm abnormalities have been reported including one case of triple tail sperm.

Keywords: Nicotine; Sperm Morphology; Male Fertility

References

  1. Mostafa R., et al. “The effect of cigarette smoking on human seminal parameters, sperm chromatin structure and condensation”. Andrologia3 (2018): e12910.
  2. Toragall MM., et al. “Association of demographic and lifestyle factors with semen quality of men with fertility problems attending infertility center in North Karnataka”. Indian Journal of Medical Specialities2 (2019): 79.
  3. Sunanda P., et al. “Prevalence of abnormal spermatozoa in tobacco chewing sub-fertile males”. Journal of Human Reproductive Sciences2 (2014): 136.
  4. Fawzy IA., et al. “Reproductive toxicity of tobacco shisha smoking on semen parameters and hormones levels among adult Egyptian men”. Research Journal of Environmental Toxicology 5 (2011): 282-292.
  5. Idris AM., et al. “Toombak use and cigarette smoking in the Sudan: estimates of prevalence in the Nile state”. Preventive Medicine4 (1998): 597-603.
  6. Kovac JR., et al. “The effects of cigarette smoking on male fertility”. Postgraduate Medicine3 (2015): 338-341.
  7. Medicine PCotASfR. “Smoking and infertility: a committee opinion”. Fertility and Sterility4 (2018): 611-618.
  8. Joesbury KA., et al. “Evidence that male smoking affects the likelihood of a pregnancy following IVF treatment: application of the modified cumulative embryo score”. Human Reproduction 6 (1998): 1506.
  9. Zitzmann MRC and Nordhoff V. “Male smokers have a decreased success rate for In vitro fertilization and intracytoplasmic sperm injection”. Fertility and Sterility3 (2003): 1550-1554.
  10. Fuentes AMA., et al. “Recent cigarette smoking and assisted reproductive technologies outcome”. Fertility and Sterility1 (2010): 89.
  11. Jensen TK JN and Punab M. “Association of in utero exposure to maternal smoking with reduced semen quality and testis size in adulthood: a cross-sectional study of 1,770 young men from the general population in five European countries”. American Journal of Epidemiology 1 (2004): 49.
  12. Storgaard L and BJ Ernst E. “Does smoking during pregnancy affect sons' sperm counts?” Epidemiology3 (2003): 278.
  13. Organization WH. “WHO laboratory manual for the examination and processing of human semen 5 edition”. Geneva, Switzerland (2010).
  14. Gardner DK., et al. “Textbook of Assisted Reproductive Technologies: Laboratory and Clinical Perspectives” (2008).
  15. Mostafa RM., et al. “The effect of cigarette smoking on human seminal parameters, sperm chromatin structure and condensation”. Andrologia3 (2018): e12910.
  16. Gojiya P., et al. “A prospective study on effects of tobacco consumption on semen parameters”. Annals of Pathology and Laboratory Medicine 5 (2018): A234-A240.
  17. Makki M., et al. “212 Tobacco chewing (Madgha) and semen quality Tobacco chewing (Madgha) and semen quality” (2018).
Citation: Ammar Mohammed Ali Mohammed., et al. “The Effect of Smoking, Hookah and Tobacco Consumption on Sperms Morphological Forms - Pilot Study”. EC Clinical and Experimental Anatomy 3.11 (2020): 11-17.

PubMed Indexed Article


EC Pharmacology and Toxicology
LC-UV-MS and MS/MS Characterize Glutathione Reactivity with Different Isomers (2,2' and 2,4' vs. 4,4') of Methylene Diphenyl-Diisocyanate.

PMID: 31143884 [PubMed]

PMCID: PMC6536005


EC Pharmacology and Toxicology
Alzheimer's Pathogenesis, Metal-Mediated Redox Stress, and Potential Nanotheranostics.

PMID: 31565701 [PubMed]

PMCID: PMC6764777


EC Neurology
Differences in Rate of Cognitive Decline and Caregiver Burden between Alzheimer's Disease and Vascular Dementia: a Retrospective Study.

PMID: 27747317 [PubMed]

PMCID: PMC5065347


EC Pharmacology and Toxicology
Will Blockchain Technology Transform Healthcare and Biomedical Sciences?

PMID: 31460519 [PubMed]

PMCID: PMC6711478


EC Pharmacology and Toxicology
Is it a Prime Time for AI-powered Virtual Drug Screening?

PMID: 30215059 [PubMed]

PMCID: PMC6133253


EC Psychology and Psychiatry
Analysis of Evidence for the Combination of Pro-dopamine Regulator (KB220PAM) and Naltrexone to Prevent Opioid Use Disorder Relapse.

PMID: 30417173 [PubMed]

PMCID: PMC6226033


EC Anaesthesia
Arrest Under Anesthesia - What was the Culprit? A Case Report.

PMID: 30264037 [PubMed]

PMCID: PMC6155992


EC Orthopaedics
Distraction Implantation. A New Technique in Total Joint Arthroplasty and Direct Skeletal Attachment.

PMID: 30198026 [PubMed]

PMCID: PMC6124505


EC Pulmonology and Respiratory Medicine
Prevalence and factors associated with self-reported chronic obstructive pulmonary disease among adults aged 40-79: the National Health and Nutrition Examination Survey (NHANES) 2007-2012.

PMID: 30294723 [PubMed]

PMCID: PMC6169793


EC Dental Science
Important Dental Fiber-Reinforced Composite Molding Compound Breakthroughs

PMID: 29285526 [PubMed]

PMCID: PMC5743211


EC Microbiology
Prevalence of Intestinal Parasites Among HIV Infected and HIV Uninfected Patients Treated at the 1o De Maio Health Centre in Maputo, Mozambique

PMID: 29911204 [PubMed]

PMCID: PMC5999047


EC Microbiology
Macrophages and the Viral Dissemination Super Highway

PMID: 26949751 [PubMed]

PMCID: PMC4774560


EC Microbiology
The Microbiome, Antibiotics, and Health of the Pediatric Population.

PMID: 27390782 [PubMed]

PMCID: PMC4933318


EC Microbiology
Reactive Oxygen Species in HIV Infection

PMID: 28580453 [PubMed]

PMCID: PMC5450819


EC Microbiology
A Review of the CD4 T Cell Contribution to Lung Infection, Inflammation and Repair with a Focus on Wheeze and Asthma in the Pediatric Population

PMID: 26280024 [PubMed]

PMCID: PMC4533840


EC Neurology
Identifying Key Symptoms Differentiating Myalgic Encephalomyelitis and Chronic Fatigue Syndrome from Multiple Sclerosis

PMID: 28066845 [PubMed]

PMCID: PMC5214344


EC Pharmacology and Toxicology
Paradigm Shift is the Normal State of Pharmacology

PMID: 28936490 [PubMed]

PMCID: PMC5604476


EC Neurology
Examining those Meeting IOM Criteria Versus IOM Plus Fibromyalgia

PMID: 28713879 [PubMed]

PMCID: PMC5510658


EC Neurology
Unilateral Frontosphenoid Craniosynostosis: Case Report and a Review of the Literature

PMID: 28133641 [PubMed]

PMCID: PMC5267489


EC Ophthalmology
OCT-Angiography for Non-Invasive Monitoring of Neuronal and Vascular Structure in Mouse Retina: Implication for Characterization of Retinal Neurovascular Coupling

PMID: 29333536 [PubMed]

PMCID: PMC5766278


EC Neurology
Longer Duration of Downslope Treadmill Walking Induces Depression of H-Reflexes Measured during Standing and Walking.

PMID: 31032493 [PubMed]

PMCID: PMC6483108


EC Microbiology
Onchocerciasis in Mozambique: An Unknown Condition for Health Professionals.

PMID: 30957099 [PubMed]

PMCID: PMC6448571


EC Nutrition
Food Insecurity among Households with and without Podoconiosis in East and West Gojjam, Ethiopia.

PMID: 30101228 [PubMed]

PMCID: PMC6086333


EC Ophthalmology
REVIEW. +2 to +3 D. Reading Glasses to Prevent Myopia.

PMID: 31080964 [PubMed]

PMCID: PMC6508883


EC Gynaecology
Biomechanical Mapping of the Female Pelvic Floor: Uterine Prolapse Versus Normal Conditions.

PMID: 31093608 [PubMed]

PMCID: PMC6513001


EC Dental Science
Fiber-Reinforced Composites: A Breakthrough in Practical Clinical Applications with Advanced Wear Resistance for Dental Materials.

PMID: 31552397 [PubMed]

PMCID: PMC6758937


EC Microbiology
Neurocysticercosis in Child Bearing Women: An Overlooked Condition in Mozambique and a Potentially Missed Diagnosis in Women Presenting with Eclampsia.

PMID: 31681909 [PubMed]

PMCID: PMC6824723


EC Microbiology
Molecular Detection of Leptospira spp. in Rodents Trapped in the Mozambique Island City, Nampula Province, Mozambique.

PMID: 31681910 [PubMed]

PMCID: PMC6824726


EC Neurology
Endoplasmic Reticulum-Mitochondrial Cross-Talk in Neurodegenerative and Eye Diseases.

PMID: 31528859 [PubMed]

PMCID: PMC6746603


EC Psychology and Psychiatry
Can Chronic Consumption of Caffeine by Increasing D2/D3 Receptors Offer Benefit to Carriers of the DRD2 A1 Allele in Cocaine Abuse?

PMID: 31276119 [PubMed]

PMCID: PMC6604646


EC Anaesthesia
Real Time Locating Systems and sustainability of Perioperative Efficiency of Anesthesiologists.

PMID: 31406965 [PubMed]

PMCID: PMC6690616


EC Pharmacology and Toxicology
A Pilot STEM Curriculum Designed to Teach High School Students Concepts in Biochemical Engineering and Pharmacology.

PMID: 31517314 [PubMed]

PMCID: PMC6741290


EC Pharmacology and Toxicology
Toxic Mechanisms Underlying Motor Activity Changes Induced by a Mixture of Lead, Arsenic and Manganese.

PMID: 31633124 [PubMed]

PMCID: PMC6800226


EC Neurology
Research Volunteers' Attitudes Toward Chronic Fatigue Syndrome and Myalgic Encephalomyelitis.

PMID: 29662969 [PubMed]

PMCID: PMC5898812


EC Pharmacology and Toxicology
Hyperbaric Oxygen Therapy for Alzheimer's Disease.

PMID: 30215058 [PubMed]

PMCID: PMC6133268


News and Events


March Issue Release

We always feel pleasure to share our updates with you all. Here, notifying you that we have successfully released the March issue of respective journals and the latest articles can be viewed on the current issue pages.

Submission Deadline for Upcoming Issue

ECronicon delightfully welcomes all the authors around the globe for effective collaboration with an article submission for the upcoming issue of respective journals. Submissions are accepted on/before April 14, 2023.

Certificate of Publication

ECronicon honors with a "Publication Certificate" to the corresponding author by including the names of co-authors as a token of appreciation for publishing the work with our respective journals.

Best Article of the Issue

Editors of respective journals will always be very much interested in electing one Best Article after each issue release. The authors of the selected article will be honored with a "Best Article of the Issue" certificate.

Certifying for Review

ECronicon certifies the Editors for their first review done towards the assigned article of the respective journals.

Latest Articles

The latest articles will be updated immediately on the articles in press page of the respective journals.