Abstract
Coronavirus disease 2019 (COVID-19) is a novel coronavirus named by the WHO as a pandemic disease as a result of its wide spread globally during the last few month. Elderly (> 60 year) patients with different comorbidities have a higher risk to contract the virus. The aim of this study is to review the recent studies regarding COVID 19 infection in elderly in terms of clinical features, risk mortality, isolation, and psychological effects that could affect their clinical management. A systematic narrative literature review of the clinical features, risks and consequences of the new COVID-19 on the elderly was carried out using online databases. Recent and related articles were retrieved mainly from Google Scholar and PubMed search. Elderly are more susceptible to develop severe forms of COVID-19 infection. The frailty in this geriatric group is attributable to their unique immune, physical and psycho-social vulnerabilities. This represent a significant risk for elderly during this COVID 19 virus pandemic.
Keywords: COVID-19; Elderly; 2019-nCoV; Clinical; Risks
References
- Pascarella G., et al. “COVID-19 diagnosis and management: a comprehensive review”. Journal of Internal Medicine 288.2 (2020): 192-206.
- Quadri SA. “COVID-19 and religious congregations: Implications for spread of novel pathogens”. International Journal of Infectious Diseases 96 (2020): 219-221.
- Liu K., et al. “Clinical features of COVID-19 in elderly patients: A comparison with young and middle-aged patients”. Journal of Infection 80.6 (2020): e14-e18.
- WHO Director-General's opening remarks at the media briefing on COVID-19 - 11 March 2020.
- Wang L., et al. “Coronavirus disease 2019 in elderly patients: Characteristics and prognostic factors based on 4-week follow-up”. Journal of Infection 80.6 (2020): 639-645.
- Huang C., et al. “Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China”. Lancet 395.10223 (2020): 497-506.
- Leung C. “Risk factors for predicting mortality in elderly patients with COVID-19: A review of clinical data in China”. Mechanisms of Ageing and Development 188 (2020): 111255.
- Tao KM., et al. “Cardiac arrest during emergency intubation in an elderly patient with confirmed coronavirus disease 2019”. The Journal of Clinical Anesthesia 66 (2020): 109951.
- Wu Z and McGoogan JM. “Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention”. The Journal of the American Medical Association (2020).
- Onder G., et al. “Case-Fatality Rate and Characteristics of Patients Dying in Relation to COVID-19 in Italy The Journal of the American Medical Association (2020).
- CDC COVID-19 Response Team. “Severe Outcomes Among Patients with Coronavirus Disease 2019 (COVID-19) - United States, February 12-March 16, 2020”. Morbidity and Mortality Weekly Report 69.12 (2020): 343-346.
- Armitage R and Nellums LB. “COVID-19 and the consequences of isolating the elderly”. Lancet Public Health 5.5 (2020): e256.
- Gerst-Emerson K and Jayawardhana J. “Loneliness as a public health issue: the impact of loneliness on health care utilization among older adults”. American Journal of Public Health 105.5 (2015): 1013-1019.
- Santini ZI., et al. “Social disconnectedness, perceived isolation, and symptoms of depression and anxiety among older Americans (NSHAP): a longitudinal mediation analysis”. Lancet Public Health 5.1 (2020): e62-e70.
- Newman MG and Zainal NH. “The value of maintaining social connections for mental health in older people”. Lancet Public Health 5.1 (2020): e12-e13.
- Käll A., et al. “Internet-Based Cognitive Behavior Therapy for Loneliness: A Pilot Randomized Controlled Trial”. Behavior Therapy 51.1 (2020): 54-68.
- Banerjee D. “Age and ageism in COVID-19': Elderly mental health-care vulnerabilities and needs”. Asian Journal of Psychiatry 51 (2020): 102154.
- Armitage R and Nellums LB. “COVID-19 and the consequences of isolating the elderly”. Lancet Public Health 5.5 (2020): e256.
- Gardner W., et al. “The Coronavirus and the Risks to the Elderly in Long- Term Care”. Journal of Aging and Social Policy 32.4-5 (2020): 310-315.
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