Mini Review
Volume 6 Issue 8 - 2020
Severe COVID-19 Infection and Hypercoagulation. A Narrative Review
Mohammed Alarbash1*, Abdulaziz Alotaibi1, Zaid Alzaid1, Abdullah Alamoudi1, Majed Alomair1, Abdullah Alabdulqadir1, Falah Alotaibi1, Omar Almakhayitah1, Hussin AlEid1, Mojtaba Al-Marzooq1, Hasan Al-Shabaan1, Omar Alharbi1, Abdullah Almeshari1, Naif Al Hamam N2 and Khaled Yassen3*
1Internship Physicians 2019 Group, College of Medicine, King Faisal University, Al-Ahsa, Hofuf, Kingdom of Saudi Arabia
2Orthopaedic/Surgery Department, College of Medicine, King Faisal University, Al-Ahsa, Hofuf, Kingdom of Saudi Arabia
3 Associate Professor, Anaesthesia/Surgery Department, College of Medicine, King Faisal University, Al-Ahsa, Hofuf, Kingdom of Saudi Arabia
*Corresponding Author: Mohammed Alarbash, Internship Physicians 2019 Group, College of Medicine, King Faisal University, Al-Ahsa, Hofuf, Kingdom of Saudi Arabia and Khaled Yassen, Associate Professor, Anaesthesia/Surgery Department, College of Medicine, King Faisal University, Al-Ahsa, Hofuf, Kingdom of Saudi Arabia.
Received: June 28, 2020; Published: July 29, 2020


Severe forms of COVID-19 infection are associated frequently with disseminated intravascular coagulation (DIC) and consumptive coagulopathy. This was found to affect the pulmonary circulation of the respiratory system and other vital organs including the liver kidney and brain. The development of intravascular thrombi, elevated D-dimer blood levels increase the risk of mortality. Anticoagulation should be administered prophylactically in mild conditions but higher therapeutic doses are required in severe forms. The early identification of coagulopathy and the continuous monitoring of the coagulation status is necessary to evaluate the effect of therapy and could improve outcome and reduce mortality. The role of thromboelastometry in the management and monitoring of this coagulopathy states remains to be evaluated.

Keywords: COVID 19; Coagulopathy; Treatment; Survival


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Citation: Mohammed Alarbash., et al. “Severe COVID-19 Infection and Hypercoagulation. A Narrative Review”. EC Anaesthesia 6.8 (2020): 03-05.

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